STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2628Conserved phage protein; Similar to Bacteriophage 186 hypothetical gp84 SWALL:CP84_BP186 (SWALL:P41062) (334 aa) fasta scores: E(): 1.7e-98, 69.69% id in 330 aa. (342 aa)    
Predicted Functional Partners:
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
 0.834
nirE
Similar to Paracoccus denitrificans uroporphyrin-III C-methyltransferase NirE SWALL:NIRE_PARDE (SWALL:Q51701) (287 aa) fasta scores: E(): 2.3e-41, 49.6% id in 256 aa, and to Vibrio cholerae uroporphyrin-III C-methyltransferase vc2561 SWALL:Q9KP18 (EMBL:AE004324) (299 aa) fasta scores: E(): 1.6e-48, 58.15% id in 239 aa; Belongs to the precorrin methyltransferase family.
 
  
 0.784
cysG1
Siroheme synthase [includes: uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.780
ECA2627
Similar to Bacteriophage P2 replication gene A protein A SWALL:VPA_BPP2 (SWALL:Q06419) (761 aa) fasta scores: E(): 4e-50, 32.96% id in 731 aa, and to Escherichia coli O6 putative replication protein for prophage c0942 SWALL:AAN79415 (EMBL:AE016758) (804 aa) fasta scores: E(): 2.1e-91, 37.13% id in 797 aa.
       0.779
cysG2
Siroheme synthase [includes: uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.779
ECA2631
Phage-related protein; Similar to Bacteriophage 186 hypothetical gp79 SWALL:CP79_BP186 (SWALL:P21682) (77 aa) fasta scores: E(): 0.00013, 40.62% id in 64 aa, and to Salmonella typhimurium fels-2 prophage: similar to protein in phage 186 stm2732 SWALL:Q8ZMS1 (EMBL:AE008824) (77 aa) fasta scores: E(): 0.0014, 35.52% id in 76 aa.
       0.778
ECA2629
Phage DNA adenine methylase; Similar to Escherichia coli, and Escherichia coli O157:H7 DNA adenine methylase Dam or b3387 or z4740 or ecs4229 SWALL:DMA_ECOLI (SWALL:P00475) (278 aa) fasta scores: E(): 1e-47, 47.68% id in 281 aa.
       0.776
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
 
 0.776
ECA2630
Phage-related protein; Similar to Salmonella typhimurium phage ST64B Sb30 SWALL:AAL25908 (EMBL:AY055382) (189 aa) fasta scores: E(): 1e-30, 50% id in 186 aa, and in parts to many other Bacteriophage exodeoxyribonuclease. e.g. Bacteriophage T4 DexA SWALL:EXOD_BPT4 (SWALL:P04536) (227 aa) fasta scores: E(): 0.00055, 26.19% id in 210 aa and to the C-terminal region of Escherichia coli O157:H7 putative exonuclease VIII, ds DNA exonuclease, 5'--> 3' specific encoded by prophage CP-933o exoo or z2037 or ecs1759 SWALL:Q8X287 (EMBL:AE005343) (823 aa) fasta scores: E(): 1.2e-27, 44.44% id in 189 aa.
       0.773
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.639
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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