STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2640Similar to Bacillus halodurans hypothetical protein Bh1883 SWALL:Q9KBP2 (EMBL:AP001513) (365 aa) fasta scores: E(): 7.6e-68, 49.45% id in 364 aa, and to Listeria innocua hypothetical protein Lin0474 SWALL:Q92EI5 (EMBL:AL596165) (366 aa) fasta scores: E(): 2e-64, 46.32% id in 367 aa. (369 aa)    
Predicted Functional Partners:
ECA2639
Putative hydantoinase; Similar to Bacillus halodurans hydantoinase bh1884 SWALL:Q9KBP1 (EMBL:AP001513) (533 aa) fasta scores: E(): 2.5e-93, 50.09% id in 519 aa, and to Enterococcus faecalis hydantoinase/oxoprolinase ef3275 SWALL:AAO82942 (EMBL:AE016957) (517 aa) fasta scores: E(): 7.4e-90, 48.55% id in 519 aa.
    0.995
ECA2641
Permease; Similar to Escherichia coli, and Escherichia coli O6 cytosine permease CodB or b0336 or c0455 SWALL:CODB_ECOLI (SWALL:P25525) (419 aa) fasta scores: E(): 2.4e-20, 28% id in 350 aa, and to Bacillus halodurans cytosine permease bh1882 SWALL:Q9KBP3 (EMBL:AP001513) (445 aa) fasta scores: E(): 1.4e-50, 36.59% id in 429 aa.
     0.907
ECA0932
Permease; Similar to Escherichia coli, and Escherichia coli O6 cytosine permease CodB or b0336 or c0455 SWALL:CODB_ECOLI (SWALL:P25525) (419 aa) fasta scores: E(): 5.8e-25, 28.73% id in 428 aa, and to Streptomyces coelicolor putative cytosine permease sco0572 or sc5g5.04C SWALL:Q93RZ8 (EMBL:AL939106) (466 aa) fasta scores: E(): 2.4e-55, 40.19% id in 413 aa.
     0.773
purD
Similar to Escherichia coli phosphoribosylamine--glycine ligase PurD or b4005 SWALL:PUR2_ECOLI (SWALL:P15640) (429 aa) fasta scores: E(): 1.2e-130, 79.67% id in 428 aa; Belongs to the GARS family.
      
 0.544
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Similar to Escherichia coli bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase] PurH or b4006 SWALL:PUR9_ECOLI (SWALL:P15639) (529 aa) fasta scores: E(): 3.7e-184, 88.84% id in 529 aa.
      
 0.544
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
      
 0.544
serB
Phosphoserine phosphatase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri phosphoserine phosphatase SerB or b4388 or z5989 or ecs5346 or sf4420 SWALL:SERB_ECOLI (SWALL:P06862) (322 aa) fasta scores: E(): 5.7e-81, 71.87% id in 320 aa.
      
 0.541
expR
Quorum-sensing transcriptional regulator; Similar to Pectobacterium carotovorum subsp. betavasculorum LuxR homolog EcbR SWALL:O30346 (EMBL:AF001050) (242 aa) fasta scores: E(): 3.8e-85, 93.38% id in 242 aa, and to Erwinia chrysanthemi transcriptional activator protein EchR SWALL:ECHR_ERWCH (SWALL:Q46967) (250 aa) fasta scores: E(): 3.6e-54, 58.61% id in 244 aa, and to Erwinia carotovora transcriptional activator protein ExpR SWALL:EXPR_ERWCA (SWALL:Q47189) (245 aa) fasta scores: E(): 1.5e-56, 61.57% id in 244 aa. Also similar to ECA1561 (67.839%% in 199 aa overlap).
     
 0.486
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
      
 0.480
flhB
Flagellar biosynthetic protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.
      
 0.477
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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