STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2649Thioredoxin reductase. (319 aa)    
Predicted Functional Partners:
ECA4212
Thioredoxin; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri thioredoxin 1 SWALL:THIO_ECOLI (SWALL:P00274) (108 aa) fasta scores: E(): 1e-36, 88.78% id in 107 aa; Belongs to the thioredoxin family.
 
 0.966
sufS
Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
 
 
 0.928
ahpC
Alkyl hydroperoxide reductase C22 protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.892
ECA1117
Probable peroxidase; Similar to Yersinia pestis putative alkyl hydroperoxide reductase subunit C AhpC or ypo3194 or y0988 SWALL:AAM84569 (EMBL:AJ414155) (200 aa) fasta scores: E(): 2.6e-76, 91.5% id in 200 aa, and to Vibrio vulnificus peroxiredoxin vv10453 SWALL:AAO08975 (EMBL:AE016798) (202 aa) fasta scores: E(): 1.4e-61, 73.5% id in 200 aa.
  
 
 0.850
ECA1267
Thioredoxin; The N-terminal region of this CDS is similar to several thioredoxinx including Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri thioredoxin 1 SWALL:THIO_ECOLI (SWALL:P00274) (108 aa) fasta scores: E(): 1.7e-14, 46.22% id in 106 aa, and to Thiobacillus ferrooxidans thioredoxin trxA SWALL:THIO_THIFE (SWALL:P52233) (108 aa) fasta scores: E(): 2.3e-14, 45.79% id in 107 aa.
 
 
 0.809
trxC
Thioredoxin 2; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri thioredoxin 2 TrxC or b2582 or c3107 or z3867 or ecs3448 or sf2644 SWALL:THI2_ECOLI (SWALL:P33636) (139 aa) fasta scores: E(): 1.5e-43, 74.81% id in 139 aa; Belongs to the thioredoxin family.
 
 0.808
ECA1220
Similar to Yersinia pestis putative thioredoxin ypo3082 or y1097 SWALL:Q8ZCB1 (EMBL:AJ414155) (289 aa) fasta scores: E(): 1e-69, 71.93% id in 285 aa, and to Escherichia coli hypothetical protein ybbn or b0492 SWALL:YBBN_ECOLI (SWALL:P77395) (284 aa) fasta scores: E(): 3.8e-68, 70.96% id in 279 aa.
  
 
 0.724
rfbI
Similar to Yersinia pestis, and Yersinia pseudotuberculosis CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase AscD or RfbI or ypo3116 or y1067 SWALL:ASCD_YERPE (SWALL:P37911) (328 aa) fasta scores: E(): 2.8e-45, 45.7% id in 326 aa, and to Salmonella typhimurium RfbI protein or stm2093 SWALL:RFBI_SALTY (SWALL:P26395) (330 aa) fasta scores: E(): 1.1e-50, 46.01% id in 326 aa.
   
 
 0.648
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.626
ECA1555
Similar to Pseudomonas aeruginosa hypothetical protein Pa2336 SWALL:Q9I1E2 (EMBL:AE004659) (446 aa) fasta scores: E(): 5.1e-44, 39.82% id in 467 aa, and to Salmonella typhimurium putative pqq enzyme repeat stm3632 SWALL:Q8ZLA7 (EMBL:AE008868) (374 aa) fasta scores: E(): 9e-07, 30.04% id in 406 aa.
  
 
 0.621
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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