node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aat | clpS | ECA2652 | ECA2657 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.797 |
aat | cydC | ECA2652 | ECA2651 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Similar to Escherichia coli transport ATP-binding protein CydC or MdrA or MdrH or SurB or b0886 SWALL:CYDC_ECOLI (SWALL:P23886) (573 aa) fasta scores: E(): 7.8e-141, 65.67% id in 571 aa. | 0.731 |
aat | cydD | ECA2652 | ECA2650 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Similar to Escherichia coli transport ATP-binding protein CydD or HtrD or b0887 SWALL:CYDD_ECOLI (SWALL:P29018) (588 aa) fasta scores: E(): 6.8e-147, 68.02% id in 588 aa. | 0.730 |
aat | ffh | ECA2652 | ECA3360 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.573 |
aat | glnA | ECA2652 | ECA0029 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Glutamine synthetase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri glutamine synthetase GlnA or b3870 or c4819 or z5406 or ecs4792 or sf3940 SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 3e-170, 90.17% id in 468 aa. | 0.628 |
aat | infA | ECA2652 | ECA2653 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.645 |
aat | proC | ECA2652 | ECA3628 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.578 |
aat | rho | ECA2652 | ECA4211 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.575 |
aat | rpoC | ECA2652 | ECA0224 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.629 |
aat | trpS | ECA2652 | ECA4087 | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.636 |
clpS | aat | ECA2657 | ECA2652 | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.797 |
cydC | aat | ECA2651 | ECA2652 | Similar to Escherichia coli transport ATP-binding protein CydC or MdrA or MdrH or SurB or b0886 SWALL:CYDC_ECOLI (SWALL:P23886) (573 aa) fasta scores: E(): 7.8e-141, 65.67% id in 571 aa. | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.731 |
cydC | cydD | ECA2651 | ECA2650 | Similar to Escherichia coli transport ATP-binding protein CydC or MdrA or MdrH or SurB or b0886 SWALL:CYDC_ECOLI (SWALL:P23886) (573 aa) fasta scores: E(): 7.8e-141, 65.67% id in 571 aa. | Similar to Escherichia coli transport ATP-binding protein CydD or HtrD or b0887 SWALL:CYDD_ECOLI (SWALL:P29018) (588 aa) fasta scores: E(): 6.8e-147, 68.02% id in 588 aa. | 0.998 |
cydC | infA | ECA2651 | ECA2653 | Similar to Escherichia coli transport ATP-binding protein CydC or MdrA or MdrH or SurB or b0886 SWALL:CYDC_ECOLI (SWALL:P23886) (573 aa) fasta scores: E(): 7.8e-141, 65.67% id in 571 aa. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.469 |
cydD | aat | ECA2650 | ECA2652 | Similar to Escherichia coli transport ATP-binding protein CydD or HtrD or b0887 SWALL:CYDD_ECOLI (SWALL:P29018) (588 aa) fasta scores: E(): 6.8e-147, 68.02% id in 588 aa. | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.730 |
cydD | cydC | ECA2650 | ECA2651 | Similar to Escherichia coli transport ATP-binding protein CydD or HtrD or b0887 SWALL:CYDD_ECOLI (SWALL:P29018) (588 aa) fasta scores: E(): 6.8e-147, 68.02% id in 588 aa. | Similar to Escherichia coli transport ATP-binding protein CydC or MdrA or MdrH or SurB or b0886 SWALL:CYDC_ECOLI (SWALL:P23886) (573 aa) fasta scores: E(): 7.8e-141, 65.67% id in 571 aa. | 0.998 |
cydD | infA | ECA2650 | ECA2653 | Similar to Escherichia coli transport ATP-binding protein CydD or HtrD or b0887 SWALL:CYDD_ECOLI (SWALL:P29018) (588 aa) fasta scores: E(): 6.8e-147, 68.02% id in 588 aa. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.470 |
ffh | aat | ECA3360 | ECA2652 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.573 |
ffh | glnA | ECA3360 | ECA0029 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Glutamine synthetase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri glutamine synthetase GlnA or b3870 or c4819 or z5406 or ecs4792 or sf3940 SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 3e-170, 90.17% id in 468 aa. | 0.671 |
ffh | proC | ECA3360 | ECA3628 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.680 |