STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2654GntR-family transcriptional regulator; Similar to Rhizobium meliloti probable rhizopine catabolism regulatory protein MocR SWALL:MOCR_RHIME (SWALL:P49309) (493 aa) fasta scores: E(): 3.2e-48, 36.95% id in 433 aa, and to Escherichia coli O157:H7 z3973 protein z3973 or ecs3534 SWALL:Q8X922 (EMBL:AE005496) (444 aa) fasta scores: E(): 2.4e-54, 43.8% id in 452 aa. (484 aa)    
Predicted Functional Partners:
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
   
  
 0.644
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
  0.640
ECA3693
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
     0.494
ECA3961
Similar to Rhizobium loti hypothetical protein Mll1199 SWALL:Q98L32 (EMBL:AP002996) (204 aa) fasta scores: E(): 3.2e-11, 29.01% id in 193 aa, and to Rhizobium meliloti putative transcriptional regulator protein rb1009 or smb21569 SWALL:Q92US9 (EMBL:AL603645) (199 aa) fasta scores: E(): 1.1e-06, 27.55% id in 196 aa.
 
    0.492
ECA2456
Probable transcriptional regulator (partial); Partial CDS. Similar to the C-terminal regions of many including Pseudomonas aeruginosa probable transcriptional regulator pa2488 SWALL:Q9I0Z4 (EMBL:AE004676) (254 aa) fasta scores: E(): 0.0017, 50% id in 42 aa, and to Vibrio vulnificus arac-type DNA-binding domain-containing protein vv20956 SWALL:AAO07868 (EMBL:AE016811) (259 aa) fasta scores: E(): 0.0035, 48.78% id in 41 aa.
  
  
 0.487
ECA2655
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
     0.480
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
       0.473
nagA
N-acetylglucosamine-6-phosphate deacetylase; Similar to Escherichia coli, and Escherichia coli O157:H7 N-acetylglucosamine-6-phosphate deacetylase NagA or b0677 or z0824 or ecs0707 SWALL:NAGA_ECOLI (SWALL:P15300) (382 aa) fasta scores: E(): 1.7e-109, 72.55% id in 379 aa.
  
  
 0.452
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.428
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.