STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2654GntR-family transcriptional regulator; Similar to Rhizobium meliloti probable rhizopine catabolism regulatory protein MocR SWALL:MOCR_RHIME (SWALL:P49309) (493 aa) fasta scores: E(): 3.2e-48, 36.95% id in 433 aa, and to Escherichia coli O157:H7 z3973 protein z3973 or ecs3534 SWALL:Q8X922 (EMBL:AE005496) (444 aa) fasta scores: E(): 2.4e-54, 43.8% id in 452 aa. (484 aa)    
Predicted Functional Partners:
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
   
  
 0.646
ECA3693
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
     0.482
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
       0.473
ECA2655
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
     0.468
ECA2456
Probable transcriptional regulator (partial); Partial CDS. Similar to the C-terminal regions of many including Pseudomonas aeruginosa probable transcriptional regulator pa2488 SWALL:Q9I0Z4 (EMBL:AE004676) (254 aa) fasta scores: E(): 0.0017, 50% id in 42 aa, and to Vibrio vulnificus arac-type DNA-binding domain-containing protein vv20956 SWALL:AAO07868 (EMBL:AE016811) (259 aa) fasta scores: E(): 0.0035, 48.78% id in 41 aa.
  
  
 0.424
ECA3961
Similar to Rhizobium loti hypothetical protein Mll1199 SWALL:Q98L32 (EMBL:AP002996) (204 aa) fasta scores: E(): 3.2e-11, 29.01% id in 193 aa, and to Rhizobium meliloti putative transcriptional regulator protein rb1009 or smb21569 SWALL:Q92US9 (EMBL:AL603645) (199 aa) fasta scores: E(): 1.1e-06, 27.55% id in 196 aa.
 
    0.424
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.