STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hcpPrismane protein homolog (hybrid-cluster protein); Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (550 aa)    
Predicted Functional Partners:
nasB
Similar to Klebsiella pneumoniae nitrite reductase [NAD(P)H] large subunit NasB SWALL:NIRB_KLEPN (SWALL:Q06458) (957 aa) fasta scores: E(): 0, 70.89% id in 962 aa; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.993
nirB
Similar to Escherichia coli nitrite reductase [NAD(P)H] large subunit NirB or b3365 SWALL:NIRB_ECOLI (SWALL:P08201) (847 aa) fasta scores: E(): 0, 80.45% id in 844 aa; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.959
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
  
  
 0.940
nrfA
Cytochrome c552 precursor; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.
 
  
 0.938
gdhA
Similar to Escherichia coli NADP-specific glutamate dehydrogenase GdhA or b1761 SWALL:DHE4_ECOLI (SWALL:P00370) (447 aa) fasta scores: E(): 7.7e-145, 85.01% id in 447 aa; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.918
nifK
Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.
     
 0.906
nifD
Similar to Klebsiella pneumoniae nitrogenase molybdenum-iron protein alpha chain NifD SWALL:NIFD_KLEPN (SWALL:P00466) (483 aa) fasta scores: E(): 2.2e-176, 87.96% id in 482 aa, and to Azotobacter vinelandii nitrogenase molybdenum-iron protein alpha chain NifD SWALL:NIFD_AZOVI (SWALL:P07328) (491 aa) fasta scores: E(): 5e-151, 73.84% id in 478 aa.
     
 0.906
glnA
Glutamine synthetase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri glutamine synthetase GlnA or b3870 or c4819 or z5406 or ecs4792 or sf3940 SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 3e-170, 90.17% id in 468 aa.
     
 0.900
hcr
Similar to Escherichia coli NADH oxidoreductase Hcr or b0872 SWALL:HCR_ECOLI (SWALL:P75824) (322 aa) fasta scores: E(): 1.3e-46, 61.14% id in 332 aa.
 
  
 0.890
hmpX
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
  
  
 0.778
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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