STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nfsASimilar to Escherichia coli oxygen-insensitive NADPH nitroreductase NfsA or MdaA or Mda18 or b0851 SWALL:NFSA_ECOLI (SWALL:P17117) (240 aa) fasta scores: E(): 7.3e-62, 65.83% id in 240 aa; Belongs to the flavin oxidoreductase frp family. (239 aa)    
Predicted Functional Partners:
rimK
Similar to Escherichia coli, and Escherichia coli O157:H7 ribosomal protein S6 modification protein rimk or b0852 or z1079 or ecs0932 SWALL:RIMK_ECOLI (SWALL:P17116) (300 aa) fasta scores: E(): 3.9e-85, 80.9% id in 288 aa.
  
  
 0.846
ECA2595
Similar to Yersinia pestis hypothetical protein Ypo1385 SWALL:Q8ZGB8 (EMBL:AJ414148) (588 aa) fasta scores: E(): 5.2e-206, 84.24% id in 584 aa, and to Escherichia coli hypothetical protein ycao or b0905 SWALL:YCAO_ECOLI (SWALL:P75838) (586 aa) fasta scores: E(): 1.9e-200, 81.84% id in 584 aa.
  
  
 0.614
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
     
 0.582
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.579
ECA0422
Putative membrane protein; Similar to Vibrio vulnificus ABC-type multidrug transport system, permease component vv12691 SWALL:AAO11038 (EMBL:AE016806) (381 aa) fasta scores: E(): 1.2e-62, 45.26% id in 391 aa.
  
  
 0.536
ECA0423
Putative membrane protein; Similar to Vibrio cholerae hypothetical protein Vc1608 vc1608 SWALL:Q9KRM8 (EMBL:AE004238) (387 aa) fasta scores: E(): 3.2e-46, 38.08% id in 365 aa.
  
  
 0.536
ECA3324
Similar to Salmonella typhi ABC transporter integral membrane protein sty0195 SWALL:Q8Z9D6 (EMBL:AL627265) (256 aa) fasta scores: E(): 1.6e-82, 83.59% id in 256 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yadh or b0128 or c0157 or z0139 or ecs0132 or sf0125 SWALL:YADH_ECOLI (SWALL:P36880) (256 aa) fasta scores: E(): 1.3e-81, 82.42% id in 256 aa.
  
  
 0.536
tadA
Putative cytidine and deoxycytidylate deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
 0.516
nirE
Similar to Paracoccus denitrificans uroporphyrin-III C-methyltransferase NirE SWALL:NIRE_PARDE (SWALL:Q51701) (287 aa) fasta scores: E(): 2.3e-41, 49.6% id in 256 aa, and to Vibrio cholerae uroporphyrin-III C-methyltransferase vc2561 SWALL:Q9KP18 (EMBL:AE004324) (299 aa) fasta scores: E(): 1.6e-48, 58.15% id in 239 aa; Belongs to the precorrin methyltransferase family.
  
 
 0.491
cysG1
Siroheme synthase [includes: uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
 
 0.491
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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