STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grxAGlutaredoxin 1; Similar to Escherichia coli, and Shigella flexneri glutaredoxin 1 GrxA or Grx or b0849 or sf0802 SWALL:GLR1_ECOLI (SWALL:P00277) (85 aa) fasta scores: E(): 6e-21, 69.88% id in 83 aa. (88 aa)    
Predicted Functional Partners:
secB
Protein-export protein; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
  
 0.863
nrdA
Ribonucleoside-diphosphate reductase 1 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.785
nrdE
Ribonucleoside-diphosphate reductase 2 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.785
ECA4354
Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
  
    0.695
nrdI
NrdI protein; Probably involved in ribonucleotide reductase function.
  
  
 0.675
gor
Similar to Escherichia coli glutathione reductase Gor SWALL:GSHR_ECOLI (SWALL:P06715) (450 aa) fasta scores: E(): 3.8e-155, 86.66% id in 450 aa and to to Yersinia pestis glutathione reductase Gor SWALL:Q8ZA43 (EMBL:AJ414160) (450 aa) fasta scores: E(): 7.8e-158, 88.66% id in 450 aa.
  
 
 0.665
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
 
  
 0.642
trxC
Thioredoxin 2; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri thioredoxin 2 TrxC or b2582 or c3107 or z3867 or ecs3448 or sf2644 SWALL:THI2_ECOLI (SWALL:P33636) (139 aa) fasta scores: E(): 1.5e-43, 74.81% id in 139 aa; Belongs to the thioredoxin family.
  
  
 0.628
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.610
ahpF
Similar to Escherichia coli alkyl hydroperoxide reductase subunit F AhpF or b0606 SWALL:AHPF_ECOLI (SWALL:P35340) (521 aa) fasta scores: E(): 3.1e-149, 78.09% id in 525 aa; EC number 1.6.4.-.
  
  
 0.603
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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