STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacCSimilar to Escherichia coli penicillin-binding protein 6 precursor DacC or b0839 SWALL:DACC_ECOLI (SWALL:P08506) (400 aa) fasta scores: E(): 3.5e-111, 71.6% id in 398 aa; Belongs to the peptidase S11 family. (401 aa)    
Predicted Functional Partners:
ftsI
Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
 
 
 0.981
mrcB
Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
 
 0.975
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
  
 
 0.974
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 0.967
dacD
Similar to Escherichia coli penicillin-binding protein 4 precursor [includes: d-alanyl-d- alanine carboxypeptidase; D-alanyl-D-alanine-endopeptidase] DacB or b3182 SWALL:PBP4_ECOLI (SWALL:P24228) (477 aa) fasta scores: E(): 2.2e-146, 76.31% id in 477 aa; deleted EC_number 3.4.99.-.
     
 0.953
mrcA
Similar to Escherichia coli penicillin-binding protein 1A MrcA or PonA or b3396 SWALL:PBPA_ECOLI (SWALL:P02918) (850 aa) fasta scores: E(): 0, 77.9% id in 851 aa.
     
 0.952
dacA
D-alanine carboxypeptidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 penicillin-binding protein 5 precursor DacA or Pfv or b0632 or c0722 or z0777 or ecs0670 SWALL:DACA_ECOLI (SWALL:P04287) (403 aa) fasta scores: E(): 4.5e-125, 79.9% id in 403 aa; Belongs to the peptidase S11 family.
     
  0.944
ECA0821
Putative exported protein; Similar to Salmonella typhimurium, and Salmonella typhi putative periplasmic protein YbiS or SWALL:Q8XFD8 (EMBL:AE008734) (306 aa) fasta scores: E(): 1.9e-74, 67.64% id in 306 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protein YbiS precursor SWALL:YBIS_ECOLI (SWALL:P75789) (306 aa) fasta scores: E(): 2.8e-74, 67.64% id in 306 aa.
    
 0.540
ECA2546
Similar to Yersinia pestis putative exported protein ypo1407 or y2763 SWALL:AAM86315 (EMBL:AJ414148) (618 aa) fasta scores: E(): 1.4e-92, 60.48% id in 615 aa, and to Vibrio cholerae hypothetical protein Vc1268 SWALL:Q9KSI8 (EMBL:AE004206) (524 aa) fasta scores: E(): 7.1e-47, 36.56% id in 495 aa.
   
 
 0.535
mreC
Rod shape-determining protein; Involved in formation and maintenance of cell shape.
 
  
 0.455
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.