STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ehpRPutative phenazine antibiotic biosynthesis protein; Required for resistance to the phenazine antibiotic. (128 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.967
ECA3869
Similar to Rhizobium meliloti putative transcription regulator protein r00227 or smc02902 SWALL:Q92SX3 (EMBL:AL591782) (230 aa) fasta scores: E(): 1.8e-52, 60.61% id in 226 aa, and to Xanthomonas axonopodis transcriptional regulator xac1298 SWALL:Q8PMX7 (EMBL:AE011760) (231 aa) fasta scores: E(): 3e-38, 50% id in 218 aa.
 
     0.729
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.597
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
    0.536
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.497
ECA2704
Putative phenazine antibiotic biosynthesis protein; Similar to Streptomyces aureofaciens oxygenase-like protein aur2G SWALL:Q93M01 (EMBL:AY033994) (285 aa) fasta scores: E(): 1.2e-38, 45.56% id in 259 aa, and to Rhizobium loti oxidoreductase of short-chain mlr1595 SWALL:Q98K81 (EMBL:AP002997) (279 aa) fasta scores: E(): 2.9e-44, 49.8% id in 255 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.471
ECA0972
Putative exported protein; Similar to Agrobacterium tumefaciens hypothetical protein atu2436 or agr_c_4418 SWALL:Q8UCP7 (EMBL:AE009191) (348 aa) fasta scores: E(): 3e-52, 43.37% id in 332 aa, and to Caulobacter crescentus hypothetical protein Cc3039 SWALL:Q9A405 (EMBL:AE005966) (335 aa) fasta scores: E(): 5.4e-20, 29.27% id in 345 aa.
  
     0.461
sdhC
Similar to Escherichia coli, and Escherichia coli O157:H7 succinate dehydrogenase cytochrome b-556 subunit SdhC or CybA or b0721 or z0875 or ecs0746 SWALL:DHSC_ECOLI (SWALL:P10446) (129 aa) fasta scores: E(): 1.1e-38, 79.06% id in 129 aa.
   
    0.448
tadA
Putative cytidine and deoxycytidylate deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
  
 0.436
ECA3557
Metallo hydrolase; Similar to Erwinia chrysanthemi metallo hydrolase precursor Meh SWALL:CAC83617 (EMBL:AJ292045) (324 aa) fasta scores: E(): 1.8e-68, 56% id in 325 aa, and to Plesiomonas sp. DLL-1 methyl parathion degrading protein SWALL:Q93SP1 (EMBL:AY029773) (341 aa) fasta scores: E(): 5e-49, 47.41% id in 310 aa. Also similar to ECA3555 (52.761% id. in 326 aa overlap).
  
 0.423
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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