STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2722Exogenous ferric siderophore TonB-dependent receptor; Similar to Vibrio cholerae iron-regulated outer membrane virulence protein precursor IrgA or vc0475 SWALL:IRGA_VIBCH (SWALL:P27772) (652 aa) fasta scores: E(): 9.1e-29, 35.05% id in 716 aa, and to Escherichia coli exogenous ferric siderophore receptor R4 SWALL:O87518 (EMBL:AF081285) (669 aa) fasta scores: E(): 2e-148, 55.45% id in 678 aa, and to Campylobacter coli ferric receptor CfrA cfrA SWALL:O07651 (EMBL:U80812) (696 aa) fasta scores: E(): 2.3e-77, 37.83% id in 703 aa. (705 aa)    
Predicted Functional Partners:
ECA0877
TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 0.659
ECA0928
TonB-like protein; Similar to Salmonella typhimurium TonB protein SWALL:TONB_SALTY (SWALL:P25945) (242 aa) fasta scores: E(): 6.8e-09, 35.93% id in 192 aa, and to Escherichia coli TonB protein SWALL:TONB_ECOLI (SWALL:P02929) (239 aa) fasta scores: E(): 6.5e-07, 37.91% id in 182 aa.
  
 0.659
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 0.659
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
  
  
 0.616
ECA3565
TonB dependent receptor; Similar to Yersinia enterocolitica ferrichrome receptor FcuA precursor fcuA SWALL:FCUA_YEREN (SWALL:Q05202) (758 aa) fasta scores: E(): 2.8e-42, 29.09% id in 787 aa, and to Escherichia coli O6 hypothetical protein c0294 or c2518 SWALL:AAN80973 (EMBL:AE016755) (721 aa) fasta scores: E(): 1.5e-160, 57.22% id in 720 aa.
  
  
 0.597
entB
Enterobactin synthetase component B (isochorismatase); Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri isochorismatase EntB or EntG or b0595 or z0737 or ecs0634 or sf0509 SWALL:ENTB_ECOLI (SWALL:P15048) (285 aa) fasta scores: E(): 1.1e-69, 63.63% id in 286 aa.
  
  
 0.593
ECA3290
Putative exported protein; Similar to Escherichia coli IroE protein SWALL:Q93K72 (EMBL:X16664) (318 aa) fasta scores: E(): 2e-18, 28.94% id in 304 aa, and to Campylobacter jejuni putative periplasmic protein cj1376 SWALL:Q9PMS4 (EMBL:AL139078) (269 aa) fasta scores: E(): 1.9e-19, 32.45% id in 265 aa.
 
  
 0.577
entE
Similar to Escherichia coli enterobactin synthetase component E [includes: 2,3-dihydroxybenzoate-AMP ligase; S-dihydroxybenzoyltransferase] EntE SWALL:ENTE_ECOLI (SWALL:P10378) (536 aa) fasta scores: E(): 1.1e-129, 64.63% id in 540 aa; EC number 7.7.58.
 
  
 0.571
ECA1272
TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 0.560
tonB-2
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 0.554
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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