STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fruASimilar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa. (563 aa)    
Predicted Functional Partners:
mtlA
Similar to Escherichia coli PTS system, mannitol-specific IIabc component MtlA or b3599 SWALL:PTMA_ECOLI (SWALL:P00550) (637 aa) fasta scores: E(): 1.1e-188, 81.63% id in 637 aa.
 
 
 0.999
ECA0342
PTS system, EIIa component; Similar to Escherichia coli O6 putative phosphotransferase system c4487 SWALL:AAN82923 (EMBL:AE016769) (156 aa) fasta scores: E(): 1.7e-44, 79.73% id in 153 aa, and to Listeria monocytogenes hypothetical protein Lmo2137 lmo2137 SWALL:Q8Y5C8 (EMBL:AL591982) (157 aa) fasta scores: E(): 2.2e-23, 48.99% id in 149 aa.
 
 0.999
fruK
1-phosphofructokinase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 1-phosphofructokinase FruK or Fpk or b2168 or c2703 or z3426 or ecs3060 or sf2253 SWALL:K1PF_ECOLI (SWALL:P23539) (312 aa) fasta scores: E(): 7.8e-108, 90.7% id in 312 aa; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.999
fruB
Similar to Escherichia coli, and Escherichia coli O157:H7 PTS system, fructose-specific IIa/Fpr component FruB or FruF or Fpr or b2169 or z3427 or ecs3061 SWALL:PTFA_ECOLI (SWALL:P24217) (376 aa) fasta scores: E(): 5.9e-97, 69.41% id in 376 aa.
 
 
 0.999
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.995
ptsH
PTS system phosphocarrier protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri phosphocarrier protein Hpr or b2415 or c2950 or z3681 or ecs3287 or stm2431 or sty2667 or t0426 or sf2470 SWALL:PTHP_ECOLI (SWALL:P07006) (85 aa) fasta scores: E(): 1e-27, 97.64% id in 85 aa.
 
 
 0.992
manX
PTS system, mannose-specific IIab component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PTS system, mannose-specific iiab component ManX or PtsL or GptB or b1817 or c2223 or z2860 or ecs2527 or sf1411 SWALL:PTNA_ECOLI (SWALL:P08186) (322 aa) fasta scores: E(): 5.5e-80, 74.84% id in 322 aa.
  
 
 0.980
ptsO
Phosphocarrier protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri phosphocarrier protein PtsO or Npr or RpoR or b3206 or c3966 or z4569 or ecs4085 or sf3246 SWALL:PTSO_ECOLI (SWALL:P33996) (90 aa) fasta scores: E(): 5.4e-26, 83.33% id in 90 aa.
  
 
 0.975
scrB
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
   
 
 0.970
ECA0339
Probable sugar-bisphosphate aldolase; Similar to Escherichia coli tagatose-1,6-bisphosphate aldolase GatY or b2096 SWALL:GATY_ECOLI (SWALL:P37192) (284 aa) fasta scores: E(): 1.8e-26, 36.36% id in 286 aa, and to Escherichia coli O6 putative aldolase c4484 SWALL:AAN82920 (EMBL:AE016769) (283 aa) fasta scores: E(): 7.5e-58, 59.01% id in 283 aa.
  
 
 0.967
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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