STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruK1-phosphofructokinase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 1-phosphofructokinase FruK or Fpk or b2168 or c2703 or z3426 or ecs3060 or sf2253 SWALL:K1PF_ECOLI (SWALL:P23539) (312 aa) fasta scores: E(): 7.8e-108, 90.7% id in 312 aa; Belongs to the carbohydrate kinase PfkB family. (312 aa)    
Predicted Functional Partners:
fruA
Similar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa.
 
 
 0.999
fruB
Similar to Escherichia coli, and Escherichia coli O157:H7 PTS system, fructose-specific IIa/Fpr component FruB or FruF or Fpr or b2169 or z3427 or ecs3061 SWALL:PTFA_ECOLI (SWALL:P24217) (376 aa) fasta scores: E(): 5.9e-97, 69.41% id in 376 aa.
 
  
 0.996
ECA0340
PTS system, IIbc component; Similar to Escherichia coli O6 putative PTS enzyme-II fructose c4485 SWALL:AAN82921 (EMBL:AE016769) (363 aa) fasta scores: E(): 4.2e-116, 84.29% id in 363 aa, and to Listeria innocua hypothetical protein Lin2240 SWALL:Q929N4 (EMBL:AL596171) (363 aa) fasta scores: E(): 5.9e-68, 51.82% id in 357 aa.
 
 
 0.993
ECA0341
PTS system, IIb component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PTS system, fructose-like-2 IIb component 1 frwb or b3950 or c4908 or z5506 or ecs4879 or sf4027 SWALL:PTWB_ECOLI (SWALL:P32673) (106 aa) fasta scores: E(): 8.5e-14, 50% id in 100 aa, and to Escherichia coli O6 pts system, fructose-like-2 IIb component 1 c4486 SWALL:AAN82922 (EMBL:AE016769) (104 aa) fasta scores: E(): 2.1e-27, 80.19% id in 101 aa.
 
 
 0.993
ECA0342
PTS system, EIIa component; Similar to Escherichia coli O6 putative phosphotransferase system c4487 SWALL:AAN82923 (EMBL:AE016769) (156 aa) fasta scores: E(): 1.7e-44, 79.73% id in 153 aa, and to Listeria monocytogenes hypothetical protein Lmo2137 lmo2137 SWALL:Q8Y5C8 (EMBL:AL591982) (157 aa) fasta scores: E(): 2.2e-23, 48.99% id in 149 aa.
 
 
 0.975
pfkA
6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
 0.937
ECA2352
Putative 6-phosphofructokinase isozyme II; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
  
  
 0.932
ECA0338
Probable sugar-bisphosphate aldolase; Similar to Lactobacillus casei D-fructose-1,6-biphosphate aldolase sorG SWALL:Q9RGG1 (EMBL:AF129168) (276 aa) fasta scores: E(): 1.9e-37, 41.97% id in 274 aa, and to Escherichia coli O6 putative aldolase c4483 SWALL:AAN82919 (EMBL:AE016769) (286 aa) fasta scores: E(): 8.4e-89, 80.06% id in 286 aa.
  
 
 0.930
ECA0339
Probable sugar-bisphosphate aldolase; Similar to Escherichia coli tagatose-1,6-bisphosphate aldolase GatY or b2096 SWALL:GATY_ECOLI (SWALL:P37192) (284 aa) fasta scores: E(): 1.8e-26, 36.36% id in 286 aa, and to Escherichia coli O6 putative aldolase c4484 SWALL:AAN82920 (EMBL:AE016769) (283 aa) fasta scores: E(): 7.5e-58, 59.01% id in 283 aa.
  
 
 0.930
fbaA
Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.930
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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