Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fruBSimilar to Escherichia coli, and Escherichia coli O157:H7 PTS system, fructose-specific IIa/Fpr component FruB or FruF or Fpr or b2169 or z3427 or ecs3061 SWALL:PTFA_ECOLI (SWALL:P24217) (376 aa) fasta scores: E(): 5.9e-97, 69.41% id in 376 aa. (377 aa)    
Predicted Functional Partners:
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 0.999
fruA
Similar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa.
 
 
 0.999
mtlA
Similar to Escherichia coli PTS system, mannitol-specific IIabc component MtlA or b3599 SWALL:PTMA_ECOLI (SWALL:P00550) (637 aa) fasta scores: E(): 1.1e-188, 81.63% id in 637 aa.
 
0.997
fruK
1-phosphofructokinase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 1-phosphofructokinase FruK or Fpk or b2168 or c2703 or z3426 or ecs3060 or sf2253 SWALL:K1PF_ECOLI (SWALL:P23539) (312 aa) fasta scores: E(): 7.8e-108, 90.7% id in 312 aa; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.997
manX
PTS system, mannose-specific IIab component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PTS system, mannose-specific iiab component ManX or PtsL or GptB or b1817 or c2223 or z2860 or ecs2527 or sf1411 SWALL:PTNA_ECOLI (SWALL:P08186) (322 aa) fasta scores: E(): 5.5e-80, 74.84% id in 322 aa.
 
 0.996
ECA0340
PTS system, IIbc component; Similar to Escherichia coli O6 putative PTS enzyme-II fructose c4485 SWALL:AAN82921 (EMBL:AE016769) (363 aa) fasta scores: E(): 4.2e-116, 84.29% id in 363 aa, and to Listeria innocua hypothetical protein Lin2240 SWALL:Q929N4 (EMBL:AL596171) (363 aa) fasta scores: E(): 5.9e-68, 51.82% id in 357 aa.
 
 
 0.994
ECA0341
PTS system, IIb component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PTS system, fructose-like-2 IIb component 1 frwb or b3950 or c4908 or z5506 or ecs4879 or sf4027 SWALL:PTWB_ECOLI (SWALL:P32673) (106 aa) fasta scores: E(): 8.5e-14, 50% id in 100 aa, and to Escherichia coli O6 pts system, fructose-like-2 IIb component 1 c4486 SWALL:AAN82922 (EMBL:AE016769) (104 aa) fasta scores: E(): 2.1e-27, 80.19% id in 101 aa.
 
 
 0.994
nagE
Similar to Escherichia coli PTS system, N-acetylglucosamine-specific IIABC component NagE or pPstN or b0679 SWALL:PTAA_ECOLI (SWALL:P09323) (648 aa) fasta scores: E(): 7.8e-62, 45.16% id in 496 aa.
 
 0.990
ECA0661
Similar to Erwinia chrysanthemi PTS system, beta-glucoside-specific IIabc component ArbF SWALL:PTBA_ERWCH (SWALL:P26207) (631 aa) fasta scores: E(): 2.4e-60, 42.76% id in 622 aa, and to Escherichia coli PTS system, beta-glucoside-specific IIabc component BglF or BglC or BglS or b3722 SWALL:PTBA_ECOLI (SWALL:P08722) (625 aa) fasta scores: E(): 6.6e-60, 42.09% id in 639 aa.
  
 0.989
ECA0860
Similar to Bacillus subtilis PTS system, beta-glucoside-specific IIabc component BglP or N17C SWALL:PTBA_BACSU (SWALL:P40739) (609 aa) fasta scores: E(): 1.1e-61, 39.06% id in 640 aa, and to Escherichia coli PTS system, arbutin-, cellobiose-, and salicin-specific IIabc component ascf or b2715 SWALL:PTDA_ECOLI (SWALL:P24241) (485 aa) fasta scores: E(): 6.6e-58, 38.55% id in 472 aa.
  
 0.989
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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