Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ECA2733Conserved hypothetical protein; Similar to Yersinia pestis putative cobalamin synthesis protein ypo1277 or y2906 SWALL:AAM86457 (EMBL:AJ414147) (327 aa) fasta scores: E(): 9.2e-90, 70.6% id in 330 aa, and to Salmonella typhimurium, and Salmonella typhi putative cobalamin synthesis protein yeir or stm2212 or sty2448 SWALL:Q8XFI7 (EMBL:AE008799) (328 aa) fasta scores: E(): 9.7e-83, 66.26% id in 329 aa. (333 aa)    
Predicted Functional Partners:
ECA2732
Putative elongation factor; Similar to Salmonella typhimurium putative elongation factor yeip or stm2211 SWALL:Q8ZNK3 (EMBL:AE008798) (267 aa) fasta scores: E(): 5.2e-62, 84.21% id in 190 aa, and to Escherichia coli O157:H7 putative elongation factor yeip or z3430 or ecs3063 SWALL:Q8XE90 (EMBL:AE005449) (275 aa) fasta scores: E(): 5.3e-62, 84.73% id in 190 aa.
      0.838
lpxT
Putative membrane-bound phosphatase; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.
     
 0.712
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.671
ECA2736
Similar to Yersinia pestis putative substrate-binding transport protein ypo1273 or y2910 SWALL:Q8ZGL6 (EMBL:AJ414147) (602 aa) fasta scores: E(): 1.5e-180, 69.6% id in 602 aa, and to Salmonella typhi putative transport system periplasmic binding protein sty2452 SWALL:Q8Z585 (EMBL:AL627273) (601 aa) fasta scores: E(): 4.8e-162, 62.29% id in 602 aa.
 
     0.652
spr
Lipoprotein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri lipoprotein Spr precursor Spr or b2175 or c2712 or z3434 or ecs3067 or sf2262 SWALL:SPR_ECOLI (SWALL:P77685) (188 aa) fasta scores: E(): 2.5e-50, 71.05% id in 190 aa.
      0.643
dksA
Dnak suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
  
  
 0.637
rpsN
30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
 
 0.621
rpmB
50S ribosomal protein L28; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 50S ribosomal protein L28 RpmB or b3637 or c4461 or z5061 or ecs4512 or sf3676 SWALL:RL28_ECOLI (SWALL:P02428) (77 aa) fasta scores: E(): 3.3e-29, 93.5% id in 77 aa; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.591
ECA1188
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yjix or b4353 or c5428 or z5952 or ecs5312 or sf4371 SWALL:YJIX_ECOLI (SWALL:P39395) (67 aa) fasta scores: E(): 4.2e-23, 83.58% id in 67 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yjix or stm4531 or sty4889 SWALL:Q8XF65 (EMBL:AE008913) (67 aa) fasta scores: E(): 1.1e-22, 83.58% id in 67 aa.
  
  
 0.577
yfeA
Similar to Yersinia pestis periplasmic chelated iron-binding protein YfeA precursor yfea or ypo2439 or y1897 SWALL:YFEA_YERPE (SWALL:Q56952) (311 aa) fasta scores: E(): 1.6e-89, 78.85% id in 298 aa; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.573
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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