STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpxTPutative membrane-bound phosphatase; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (233 aa)    
Predicted Functional Partners:
ECA0044
Similar to Yersinia pestis putative membrane protein ypo4013 SWALL:Q8ZA13 (EMBL:AJ414160) (563 aa) fasta scores: E(): 5e-173, 75.4% id in 557 aa, and to Escherichia coli membrane-protein YhjW SWALL:YHJW_ECOLI (SWALL:P37661) (563 aa) fasta scores: E(): 7.5e-150, 64.99% id in 557 aa.
  
  
 0.931
arnT
Dolichyl-phosphate-mannose-protein mannosyltransferase-family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.
 
  
 0.931
pagP
Putative antimicrobial peptide resistance and lipid A acylation protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
  
  
 0.923
pmrC
Putative sulfatase; Similar to Pectobacterium carotovorum subsp. carotovorum putative cytoplasmic membrane protein PmrC pmrC SWALL:CAE47078 (EMBL:AJ583007) (548 aa) fasta scores: E(): 4.1e-202, 93.79% id in 548 aa, and to Escherichia coli hypothetical protein yjdb or b4114 SWALL:YJDB_ECOLI (SWALL:P30845) (547 aa) fasta scores: E(): 1.2e-128, 59.29% id in 538 aa.
     
 0.918
msbB
Lipid A biosynthesis (KDO)2-(lauroyl)-lipid iva acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.
    
 0.911
ECA3332
Similar to Yersinia pestis putative exported protein ypo3410 or y0776 SWALL:Q8ZBJ9 (EMBL:AJ414157) (115 aa) fasta scores: E(): 1.6e-30, 69.29% id in 114 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein yacc precursor yacc or b0122 or c0151 SWALL:YACC_ECOLI (SWALL:P23838) (115 aa) fasta scores: E(): 1.6e-27, 64.34% id in 115 aa.
  
     0.723
rcsF
Stimulator of colanic acid capsule synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
  
     0.721
ECA2255
Putative exported protein; Similar to Escherichia coli O157:H7 orf, hypothetical protein z2573 or ecs2292 SWALL:Q8X798 (EMBL:AE005382) (102 aa) fasta scores: E(): 1.2e-14, 55.44% id in 101 aa, and to Salmonella typhimurium putative outer membrane protein ynfd or stm1500 SWALL:Q8ZPJ5 (EMBL:AE008765) (102 aa) fasta scores: E(): 5.2e-14, 56.98% id in 93 aa.
  
     0.701
ppdA
Similar to Escherichia coli prepilin peptidase dependent protein A precursor PpdA or b2826 SWALL:PPDA_ECOLI (SWALL:P33554) (156 aa) fasta scores: E(): 5.2e-19, 40% id in 150 aa, and to Salmonella typhimurium prepilin peptidase dependent protein a, putative component in type IVpilin biogenesis ppda or stm3000 SWALL:Q8ZMB0 (EMBL:AE008837) (156 aa) fasta scores: E(): 2.7e-20, 39.35% id in 155 aa.
  
     0.700
ECA2733
Conserved hypothetical protein; Similar to Yersinia pestis putative cobalamin synthesis protein ypo1277 or y2906 SWALL:AAM86457 (EMBL:AJ414147) (327 aa) fasta scores: E(): 9.2e-90, 70.6% id in 330 aa, and to Salmonella typhimurium, and Salmonella typhi putative cobalamin synthesis protein yeir or stm2212 or sty2448 SWALL:Q8XFI7 (EMBL:AE008799) (328 aa) fasta scores: E(): 9.7e-83, 66.26% id in 329 aa.
     
 0.691
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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