STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bcrSimilar to Escherichia coli bicyclomycin resistance protein Bcr or BicA or BicR or Sur or SuxA or b2182 SWALL:BCR_ECOLI (SWALL:P28246) (396 aa) fasta scores: E(): 4.4e-110, 69.13% id in 392 aa. (396 aa)    
Predicted Functional Partners:
rsuA
Ribosomal small subunit pseudouridine synthase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribosomal small subunit pseudouridine synthase A RsuA or b2183 or c2720 or z3442 or ecs3075 or sf2270 SWALL:RSUA_ECOLI (SWALL:P33918) (231 aa) fasta scores: E(): 5.3e-75, 78.26% id in 230 aa; ribosomal small subunit pseudouridine synthase a.
       0.667
cyaA
Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family.
      
 0.498
dksA
Dnak suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
      
 0.496
queF
Putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
      
 0.494
ECA1153
Putative exported protein; Similar to Salmonella typhimurium, and Salmonella typhi putative DNA uptake protein and related dna-binding proteins ybav or stm0453 or sty0495 SWALL:Q8XGV0 (EMBL:AE008716) (124 aa) fasta scores: E(): 5.3e-15, 48.78% id in 123 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein ybav precursor ybav or b0442 or sf0387 SWALL:AAN42043 (EMBL:AE000150) (123 aa) fasta scores: E(): 2.8e-13, 49.19% id in 124 aa.
   
  
 0.489
ECA1449
Putative chorismate mutase; Similar to Erwinia herbicola monofunctional chorismate mutase precursor AroQ SWALL:CHMU_ERWHE (SWALL:P42517) (181 aa) fasta scores: E(): 1.2e-18, 38.88% id in 180 aa, and to Yersinia pestis putative chorismate mutase ypo1353 or y2828 SWALL:Q8ZGE8 (EMBL:AJ414147) (186 aa) fasta scores: E(): 5.3e-17, 34.83% id in 178 aa.
   
 
 0.471
hrpX
Two-component sensor kinase; Similar to Erwinia chrysanthemi HrpX SWALL:Q8KUM4 (EMBL:AF448202) (450 aa) fasta scores: E(): 3.4e-115, 68.25% id in 441 aa, and to Erwinia amylovora sensor kinase HrpX SWALL:Q9X3S8 (EMBL:AF083877) (494 aa) fasta scores: E(): 9.5e-100, 56.13% id in 481 aa.
     
 0.470
nahM
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
      
 0.468
scrY
Putative sucrose porin; Similar to Klebsiella pneumoniae sucrose porin precursor ScrY SWALL:SCRY_KLEPN (SWALL:P27218) (505 aa) fasta scores: E(): 1.3e-125, 63.33% id in 510 aa, and to Erwinia amylovora porin ScrY SWALL:Q9F4A0 (EMBL:AJ250722) (514 aa) fasta scores: E(): 8.5e-118, 62.57% id in 521 aa.
      
 0.467
lacZ
Beta-galactosidase; Similar to Escherichia coli beta-galactosidase LacZ or b0344 SWALL:BGAL_ECOLI (SWALL:P00722) (1023 aa) fasta scores: E(): 0, 64.84% id in 1024 aa; Belongs to the glycosyl hydrolase 2 family.
      
 0.465
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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