STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2747Similar to Escherichia coli 37 kDa nucleoid-associated protein yejk or b2186 SWALL:NA37_ECOLI (SWALL:P33920) (334 aa) fasta scores: E(): 2.6e-104, 80.53% id in 334 aa. (336 aa)    
Predicted Functional Partners:
ECA2749
Similar to Salmonella typhi putative sulphatase sty2466 SWALL:Q8Z579 (EMBL:AL627273) (586 aa) fasta scores: E(): 5.5e-146, 60.47% id in 587 aa, and to Shigella flexneri putative sulfatase yejm or sf2275 SWALL:AAN43794 (EMBL:AE015243) (586 aa) fasta scores: E(): 3.6e-143, 59.11% id in 587 aa.
 
   
 0.889
ECA2748
Similar to Yersinia pestis hypothetical protein Ypo1261 SWALL:Q8ZGM6 (EMBL:AJ414147) (75 aa) fasta scores: E(): 4.5e-22, 85.52% id in 76 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yejl or stm2227 or sty2465 SWALL:Q8XEL6 (EMBL:AE008799) (75 aa) fasta scores: E(): 1.6e-19, 78.94% id in 76 aa; Belongs to the UPF0352 family.
 
   
 0.769
yihI
Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.746
ECA3038
Putative membrane protein; Similar to Yersinia pestis hypothetical protein ypo2564 or y1623 SWALL:YP64_YERPE (SWALL:Q8ZDJ8) (151 aa) fasta scores: E(): 2.9e-52, 79.47% id in 151 aa, and to Photorhabdus temperata b2295 SWALL:AAN08358 (EMBL:AY137386) (151 aa) fasta scores: E(): 1.6e-45, 69.53% id in 151 aa.
  
     0.705
ECA0978
Putative DNA-binding protein; Similar to Escherichia coli hypothetical protein yggl or b2959 SWALL:YGGL_ECOLI (SWALL:P38521) (108 aa) fasta scores: E(): 4e-30, 66.66% id in 108 aa, and to Shigella flexneri orf, conserved hypothetical protein yggl or sf2956 SWALL:AAN44437 (EMBL:AE015308) (118 aa) fasta scores: E(): 5e-30, 66.66% id in 108 aa.
  
     0.614
rlmM
Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
  
    0.583
ECA4231
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri protein yife or b3764 or c4686 or z5276 or ecs4699 or sf3840 SWALL:AAN45278 (EMBL:M87049) (112 aa) fasta scores: E(): 2.1e-36, 79.46% id in 112 aa, and to Yersinia pestis hypothetical protein Ypo3903 SWALL:Q8ZAA8 (EMBL:AJ414159) (112 aa) fasta scores: E(): 7.3e-36, 81.25% id in 112 aa.
  
     0.564
slyX
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 SlyX protein slyx or b3348 or c4122 or z4706 or ecs4199 SWALL:SLYX_ECOLI (SWALL:P30857) (72 aa) fasta scores: E(): 5.2e-12, 59.72% id in 72 aa, and to Yersinia pestis host factor for lysis of phix174 infection SlyX or y3976 SWALL:AAM87520 (EMBL:AE014001) (72 aa) fasta scores: E(): 1.5e-13, 63.88% id in 72 aa; Belongs to the SlyX family.
  
   
 0.543
metJ
Repressor of the methionine regulon; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
    0.532
seqA
Putative negative regulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
    0.512
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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