Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prtFSimilar to Erwinia chrysanthemi proteases secretion protein PrtF precursor SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 3.6e-123, 73.25% id in 445 aa. Also similar to ECA1534 (48.956% in 431 aa overlap. (448 aa)    
Predicted Functional Partners:
prtE
Similar to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 9.7e-110, 72.33% id in 441 aa. Also similar to ECA1535 (47.529% in 425 aa overlap.
 
 0.977
prtD
Similar to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 1.2e-155, 74.6% id in 575 aa. Also similar to ECA1536 (58.719% in 562 aa overlap.
 
  
 0.941
prtW
Metalloprotease; Similar to Pectobacterium carotovorum subsp. carotovorum metalloprotease PrtW SWALL:Q9RB20 (EMBL:AF141295) (473 aa) fasta scores: E(): 4.7e-142, 84.51% id in 478 aa, and to Erwinia chrysanthemi secreted protease C precursor PrtC SWALL:PRTX_ERWCH (SWALL:P19144) (478 aa) fasta scores: E(): 5.8e-116, 66.03% id in 471 aa.
 
  
 0.910
hasE
HlyD family secretion protein; Similar to Pseudomonas fluorescens membrane fusion protein HasE SWALL:Q9RHT1 (EMBL:AB023289) (443 aa) fasta scores: E(): 2.5e-67, 52.28% id in 438 aa, and to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 3.8e-62, 46.03% id in 441 aa. Also similar to ECA2782 (47.529% identity in 425 aa overlap).
 
 0.797
macA
Similar to Escherichia coli macrolide-specific efflux protein MacA precursor MacA or b0878 SWALL:MACA_ECOLI (SWALL:P75830) (371 aa) fasta scores: E(): 8.9e-30, 37.17% id in 390 aa, and to Yersinia pestis putative HlyD family secretion protein ypo2999 or y1481 SWALL:AAM85052 (EMBL:AJ414154) (401 aa) fasta scores: E(): 3.8e-78, 64.69% id in 405 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.738
ECA2930
HlyD-family secretion protein; Similar to Pseudomonas putida RND efflux membrane fusion protein pp3301 SWALL:AAN68908 (EMBL:AE016786) (367 aa) fasta scores: E(): 2.8e-81, 70.1% id in 368 aa, and to Xylella fastidiosa component of multidrug efflux system xf2084 SWALL:Q9PBQ6 (EMBL:AE004023) (368 aa) fasta scores: E(): 3.9e-75, 63.95% id in 369 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.738
mdtA
Similar to Salmonella typhimurium putative HlyD family secretion protein stm2126 SWALL:Q8ZNQ3 (EMBL:AE008794) (413 aa) fasta scores: E(): 1.9e-84, 63.27% id in 403 aa, and to Salmonella typhi putative efflux system protein sty2339 SWALL:Q8Z5F8 (EMBL:AL627273) (413 aa) fasta scores: E(): 2.2e-84, 63.27% id in 403 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.738
ECA0801
Putative exported protein; Similar to Vibrio cholerae hypothetical protein vc0913 SWALL:Q9KTI9 (EMBL:AE004175) (352 aa) fasta scores: E(): 2.3e-10, 26.29% id in 232 aa, and to Shewanella oneidensis HlyD family secretion protein so3483 SWALL:AAN56476 (EMBL:AE015784) (369 aa) fasta scores: E(): 2.4e-09, 25.49% id in 251 aa. Note that there are no significant database matches to enterobacterial species; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.727
inh
Protease inhibitor; Similar to Pectobacterium carotovorum subsp. carotovorum protease inhibitor Inh SWALL:Q9RB19 (EMBL:AF141295) (103 aa) fasta scores: E(): 4.8e-37, 89.32% id in 103 aa, and to Erwinia chrysanthemi proteinase inhibitor precursor Inh SWALL:INH_ERWCH (SWALL:P18958) (120 aa) fasta scores: E(): 7.6e-21, 57.28% id in 103 aa.
  
  
 0.723
emrA
Similar to Erwinia chrysanthemi EmrA protein EmrA SWALL:Q93KB1 (EMBL:AJ410307) (391 aa) fasta scores: E(): 7.9e-104, 72.63% id in 391 aa, and to Escherichia coli multidrug resistance protein A EmrA or b2685 SWALL:EMRA_ECOLI (SWALL:P27303) (390 aa) fasta scores: E(): 5.7e-94, 68.28% id in 391 aa.
  
 0.687
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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