Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prtESimilar to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 9.7e-110, 72.33% id in 441 aa. Also similar to ECA1535 (47.529% in 425 aa overlap. (442 aa)    
Predicted Functional Partners:
prtF
Similar to Erwinia chrysanthemi proteases secretion protein PrtF precursor SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 3.6e-123, 73.25% id in 445 aa. Also similar to ECA1534 (48.956% in 431 aa overlap.
 
 0.977
prtD
Similar to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 1.2e-155, 74.6% id in 575 aa. Also similar to ECA1536 (58.719% in 562 aa overlap.
 
  
 0.966
ECA3268
Putative toxin secretion ATP-binding protein; Similar to Actinobacillus pleuropneumoniae Rtx-I toxin determinant B Apxib or clyib or hlyib or appB SWALL:RT1B_ACTPL (SWALL:P26760) (707 aa) fasta scores: E(): 1.1e-55, 28.05% id in 695 aa, and to Pseudomonas putida toxin secretion ATP-binding protein pp0167 SWALL:AAN65800 (EMBL:AE016774) (718 aa) fasta scores: E(): 1.1e-188, 69.83% id in 706 aa, and to Pasteurella haemolytica leukotoxin secretion ATP-binding protein lktB SWALL:HLYB_PASHA (SWALL:P16532) (708 aa) fasta scores: E(): 1.1e-55, 27.84% id in 686 aa.
 
 0.918
prtW
Metalloprotease; Similar to Pectobacterium carotovorum subsp. carotovorum metalloprotease PrtW SWALL:Q9RB20 (EMBL:AF141295) (473 aa) fasta scores: E(): 4.7e-142, 84.51% id in 478 aa, and to Erwinia chrysanthemi secreted protease C precursor PrtC SWALL:PRTX_ERWCH (SWALL:P19144) (478 aa) fasta scores: E(): 5.8e-116, 66.03% id in 471 aa.
 
  
 0.913
ECA1097
Similar to Pseudomonas putida protein secretion ABC efflux system, permease and ATP-binding protein pp0804 SWALL:AAN66429 (EMBL:AE016777) (722 aa) fasta scores: E(): 5.9e-111, 46.31% id in 691 aa, and to Salmonella typhi putative type i secretion protein, ATP-binding protein sty2877 SWALL:Q8Z4H9 (EMBL:AL627276) (718 aa) fasta scores: E(): 1.4e-103, 42.34% id in 692 aa.
 
 0.894
aggA
Agglutination protein; Similar to Pseudomonas putida agglutination protein precursor AggA SWALL:Q52018 (EMBL:M64540) (452 aa) fasta scores: E(): 4e-73, 47.27% id in 440 aa, and to Vibrio cholerae agglutination protein vc1621 SWALL:Q9KRL6 (EMBL:AE004240) (445 aa) fasta scores: E(): 1.6e-51, 36.58% id in 421 aa.
 
 0.853
hasF
Similar to Pseudomonas fluorescens outer membrane protein HasF SWALL:Q9RHT0 (EMBL:AB023289) (442 aa) fasta scores: E(): 1.5e-85, 54.96% id in 433 aa, and to Erwinia chrysanthemi proteases secretion protein PrtF precursor prtF SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 2.1e-75, 48.82% id in 424 aa. Also similar to ECA2781 (48.956% identity in 431 aa overlap).
 
 0.838
hasD
Type I secretion ATP-binding protein; Similar to Pseudomonas fluorescens ABC protein HasD SWALL:Q9RHT2 (EMBL:AB023289) (580 aa) fasta scores: E(): 2.6e-129, 65.58% id in 584 aa, and to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 5.2e-113, 59.47% id in 570 aa. Also similar to ECA2783 (58.719% id. in 562 aa overlap).
 
  
 0.817
inh
Protease inhibitor; Similar to Pectobacterium carotovorum subsp. carotovorum protease inhibitor Inh SWALL:Q9RB19 (EMBL:AF141295) (103 aa) fasta scores: E(): 4.8e-37, 89.32% id in 103 aa, and to Erwinia chrysanthemi proteinase inhibitor precursor Inh SWALL:INH_ERWCH (SWALL:P18958) (120 aa) fasta scores: E(): 7.6e-21, 57.28% id in 103 aa.
  
  
 0.726
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.670
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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