STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
inhProtease inhibitor; Similar to Pectobacterium carotovorum subsp. carotovorum protease inhibitor Inh SWALL:Q9RB19 (EMBL:AF141295) (103 aa) fasta scores: E(): 4.8e-37, 89.32% id in 103 aa, and to Erwinia chrysanthemi proteinase inhibitor precursor Inh SWALL:INH_ERWCH (SWALL:P18958) (120 aa) fasta scores: E(): 7.6e-21, 57.28% id in 103 aa. (103 aa)    
Predicted Functional Partners:
prtW
Metalloprotease; Similar to Pectobacterium carotovorum subsp. carotovorum metalloprotease PrtW SWALL:Q9RB20 (EMBL:AF141295) (473 aa) fasta scores: E(): 4.7e-142, 84.51% id in 478 aa, and to Erwinia chrysanthemi secreted protease C precursor PrtC SWALL:PRTX_ERWCH (SWALL:P19144) (478 aa) fasta scores: E(): 5.8e-116, 66.03% id in 471 aa.
  
 
 0.983
prtD
Similar to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 1.2e-155, 74.6% id in 575 aa. Also similar to ECA1536 (58.719% in 562 aa overlap.
  
  
 0.818
prtE
Similar to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 9.7e-110, 72.33% id in 441 aa. Also similar to ECA1535 (47.529% in 425 aa overlap.
  
  
 0.726
prtF
Similar to Erwinia chrysanthemi proteases secretion protein PrtF precursor SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 3.6e-123, 73.25% id in 445 aa. Also similar to ECA1534 (48.956% in 431 aa overlap.
  
  
 0.723
ECA0732
Similar to Yersinia pestis putative exported protein ypo3993 SWALL:Q8ZA27 (EMBL:AJ414160) (159 aa) fasta scores: E(): 4.2e-40, 67.08% id in 158 aa.
   
 
 0.644
hrpN
Harpin; Similar to Pectobacterium carotovorum subsp. carotovorum HrpN SWALL:Q93FY8 (EMBL:AF302656) (356 aa) fasta scores: E(): 4e-79, 91.37% id in 371 aa, and to Erwinia carotovora harpin hrpN SWALL:HRPN_ERWCA (SWALL:Q47279) (356 aa) fasta scores: E(): 2.2e-78, 90.83% id in 371 aa.
   
 
 0.644
ECA3266
Similar to Ralstonia solanacearum putative hemagglutinin/hemolysin-related protein rsp1180 or rs05070 SWALL:Q8XQP2 (EMBL:AL646083) (4106 aa) fasta scores: E(): 3.1e-134, 29.53% id in 4320 aa, and to Aeromonas salmonicida Rtx protein Asx SWALL:Q9L800 (EMBL:AF218037) (2747 aa) fasta scores: E(): 1.3e-47, 28.2% id in 2822 aa.
   
 
 0.644
sdhE
Conserved hypothetical protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
      
 0.530
cas6f
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Processes pre-crRNA into individual crRNA units.
      
 0.499
queF
Putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
      
 0.469
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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