STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prtWMetalloprotease; Similar to Pectobacterium carotovorum subsp. carotovorum metalloprotease PrtW SWALL:Q9RB20 (EMBL:AF141295) (473 aa) fasta scores: E(): 4.7e-142, 84.51% id in 478 aa, and to Erwinia chrysanthemi secreted protease C precursor PrtC SWALL:PRTX_ERWCH (SWALL:P19144) (478 aa) fasta scores: E(): 5.8e-116, 66.03% id in 471 aa. (469 aa)    
Predicted Functional Partners:
inh
Protease inhibitor; Similar to Pectobacterium carotovorum subsp. carotovorum protease inhibitor Inh SWALL:Q9RB19 (EMBL:AF141295) (103 aa) fasta scores: E(): 4.8e-37, 89.32% id in 103 aa, and to Erwinia chrysanthemi proteinase inhibitor precursor Inh SWALL:INH_ERWCH (SWALL:P18958) (120 aa) fasta scores: E(): 7.6e-21, 57.28% id in 103 aa.
  
 
 0.983
prtD
Similar to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 1.2e-155, 74.6% id in 575 aa. Also similar to ECA1536 (58.719% in 562 aa overlap.
 
 
 0.946
prtE
Similar to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 9.7e-110, 72.33% id in 441 aa. Also similar to ECA1535 (47.529% in 425 aa overlap.
 
  
 0.913
prtF
Similar to Erwinia chrysanthemi proteases secretion protein PrtF precursor SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 3.6e-123, 73.25% id in 445 aa. Also similar to ECA1534 (48.956% in 431 aa overlap.
 
  
 0.910
hasD
Type I secretion ATP-binding protein; Similar to Pseudomonas fluorescens ABC protein HasD SWALL:Q9RHT2 (EMBL:AB023289) (580 aa) fasta scores: E(): 2.6e-129, 65.58% id in 584 aa, and to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 5.2e-113, 59.47% id in 570 aa. Also similar to ECA2783 (58.719% id. in 562 aa overlap).
 
 
 0.814
hasE
HlyD family secretion protein; Similar to Pseudomonas fluorescens membrane fusion protein HasE SWALL:Q9RHT1 (EMBL:AB023289) (443 aa) fasta scores: E(): 2.5e-67, 52.28% id in 438 aa, and to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 3.8e-62, 46.03% id in 441 aa. Also similar to ECA2782 (47.529% identity in 425 aa overlap).
 
  
 0.740
prt1
Extracellular metalloprotease; Extracellular zinc metalloprotease.
  
  
 0.740
ECA0980
Autotransporter; Similar to Pseudomonas fluorescens serine protease homologue PspB SWALL:Q9ZNI5 (EMBL:AB015053) (1036 aa) fasta scores: E(): 1.6e-25, 28.66% id in 1106 aa, and to Serratia marcescens extracellular serine protease precursor SWALL:PRTT_SERMA (SWALL:P29805) (1045 aa) fasta scores: E(): 1.1e-16, 25.6% id in 1082 aa.
  
 
 0.727
ECA3268
Putative toxin secretion ATP-binding protein; Similar to Actinobacillus pleuropneumoniae Rtx-I toxin determinant B Apxib or clyib or hlyib or appB SWALL:RT1B_ACTPL (SWALL:P26760) (707 aa) fasta scores: E(): 1.1e-55, 28.05% id in 695 aa, and to Pseudomonas putida toxin secretion ATP-binding protein pp0167 SWALL:AAN65800 (EMBL:AE016774) (718 aa) fasta scores: E(): 1.1e-188, 69.83% id in 706 aa, and to Pasteurella haemolytica leukotoxin secretion ATP-binding protein lktB SWALL:HLYB_PASHA (SWALL:P16532) (708 aa) fasta scores: E(): 1.1e-55, 27.84% id in 686 aa.
 
  
 0.726
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
  
  
 0.705
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (18%) [HD]