STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2794Putative exported protein; Similar to Thermoanaerobacter tengcongensis major membrane immunogen tte2480 SWALL:Q8R7D5 (EMBL:AE013189) (138 aa) fasta scores: E(): 0.61, 35% id in 140 aa, and to Clostridium acetobutylicum uncharacterized conserved protein cac2767 SWALL:Q97FH2 (EMBL:AE007774) (133 aa) fasta scores: E(): 0.0033, 31.86% id in 91 aa. (118 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.961
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.958
sdhC
Similar to Escherichia coli, and Escherichia coli O157:H7 succinate dehydrogenase cytochrome b-556 subunit SdhC or CybA or b0721 or z0875 or ecs0746 SWALL:DHSC_ECOLI (SWALL:P10446) (129 aa) fasta scores: E(): 1.1e-38, 79.06% id in 129 aa.
  
 0.888
fumA
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.827
sdhB
Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB or b0724 SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 6.3e-88, 87.81% id in 238 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.798
frdB
Fumarate reductase iron-sulfur protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri fumarate reductase iron-sulfur protein frdB or b4153 or c5241 or z5760 or ecs5134 or sf4311 SWALL:FRDB_ECOLI (SWALL:P00364) (243 aa) fasta scores: E(): 2.8e-84, 85.24% id in 244 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.798
ECA0911
Putative exported protein; Similar to Fusobacterium nucleatum hypothetical protein Fn0656 SWALL:Q8RFN5 (EMBL:AE010576) (126 aa) fasta scores: E(): 0.065, 32.14% id in 112 aa, and to Methanosarcina acetivorans na+-transporting NADH:ubiquinone oxidoreductase, subunit 3 Nqr3 or ma0661 SWALL:Q8TSY2 (EMBL:AE010727) (188 aa) fasta scores: E(): 5.6, 31.64% id in 79 aa.
 
     0.738
sdhD
Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
 
 0.729
napF
Ferredoxin-type protein; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.
  
 
 0.678
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.676
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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