Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
moaDSimilar to Escherichia coli molybdopterin converting factor subunit 1 MoaD or ChlA4 or ChlM or b0784 SWALL:MOAD_ECOLI (SWALL:P30748) (81 aa) fasta scores: E(): 3.2e-19, 67.9% id in 81 aa. (81 aa)    
Predicted Functional Partners:
moaE
Similar to Escherichia coli molybdopterin converting factor subunit 2 MoaE or ChlA5 or b0785 SWALL:MOAE_ECOLI (SWALL:P30749) (149 aa) fasta scores: E(): 6.1e-45, 76.51% id in 149 aa.
 
 0.999
moeB
Similar to Escherichia coli molybdopterin biosynthesis protein MoeB or ChlN or b0826 SWALL:MOEB_ECOLI (SWALL:P12282) (249 aa) fasta scores: E(): 1.1e-66, 71.37% id in 248 aa.
  
 0.997
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 
 0.996
moaB
Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
 
 
 0.976
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 
 0.950
thiF
Thiamine biosynthesis adenylyltransferase; Similar to Escherichia coli adenylyltransferase ThiF or b3992 SWALL:THIF_ECOLI (SWALL:P30138) (251 aa) fasta scores: E(): 7e-59, 60.56% id in 246 aa.
  
 0.897
moeA
Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.802
mog
Molybdopterin biosynthesis protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri molybdopterin biosynthesis Mog protein Mog or MogA or ChlG or b0009 or z0009 or ecs0009 or sf0010 SWALL:MOG_ECOLI (SWALL:P28694) (195 aa) fasta scores: E(): 2e-61, 85.12% id in 195 aa.
 
 
 0.778
sirA
SirA protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
 
 
 
 0.626
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 
  
 0.612
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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