STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2819Hypothetical protein; Weakly similar to Bacillus subtilis hypothetical protein YsfE SWALL:P94533 (EMBL:Z75208) (80 aa) fasta scores: E(): 0.92, 30% id in 60 aa. (143 aa)    
Predicted Functional Partners:
ECA3160
Similar to Salmonella typhimurium putative transcriptional regulator stm2195 SWALL:Q8ZNL4 (EMBL:AE008798) (129 aa) fasta scores: E(): 3.8e-14, 38.68% id in 137 aa, and to Salmonella typhi putative DNA-binding protein sty2429 SWALL:Q8Z5A0 (EMBL:AL627273) (129 aa) fasta scores: E(): 4.4e-14, 38.68% id in 137 aa.
  
     0.675
ECA1659
Probable plasmid-related protein; Similar to Lactococcus lactis nicking enzyme SWALL:O87207 (EMBL:AE001272) (680 aa) fasta scores: E(): 2.9e-20, 33.77% id in 302 aa, and to Escherichia coli O6 hypothetical protein c2397 SWALL:AAN80856 (EMBL:AE016762) (500 aa) fasta scores: E(): 2.9e-119, 64.98% id in 477 aa, and to Thiobacillus ferrooxidans mobilization protein MobL mobL SWALL:MOBL_THIFE (SWALL:P20085) (378 aa) fasta scores: E(): 3.7e-09, 28.23% id in 294 aa.
  
    0.629
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
  
 0.608
uvrB
Excision nuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissoc [...]
       0.595
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 
 0.547
ECA1674
Similar to Pyrococcus furiosus hypothetical protein Pf0664 SWALL:Q8U312 (EMBL:AE010187) (102 aa) fasta scores: E(): 2.1e-05, 31.81% id in 88 aa.
  
     0.533
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
  
 0.516
ECA2242
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
  
     0.490
ECA2898
Similar to Xanthomonas axonopodis plasmid mobilization protein MobL or xac3260 SWALL:Q8PHJ4 (EMBL:AE011971) (530 aa) fasta scores: E(): 4.1e-17, 32.84% id in 274 aa, and to Rhizobium loti probable conjugal transfer protein, TraA mll0964 SWALL:Q98LM6 (EMBL:AP002996) (1015 aa) fasta scores: E(): 1.6e-21, 36.1% id in 277 aa, and to Staphylococcus aureus orit nickase NeS neS SWALL:O87361 (EMBL:AF051917) (665 aa) fasta scores: E(): 2.4e-16, 33.99% id in 203 aa.
  
    0.488
nifL
Similar to Klebsiella pneumoniae nitrogen fixation regulatory protein NifL SWALL:NIFL_KLEPN (SWALL:P06772) (495 aa) fasta scores: E(): 2e-130, 66.46% id in 495 aa, and to Pantoea agglomerans NifL protein NifL SWALL:Q57340 (EMBL:X99694) (495 aa) fasta scores: E(): 5.8e-122, 61.21% id in 495 aa.
  
     0.484
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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