Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ECA2849Metallo-beta-lactamase; Similar to Xanthomonas maltophilia metallo-beta-lactamase precursor BlaS SWALL:Q9F238 (EMBL:AJ291672) (290 aa) fasta scores: E(): 9.3e-15, 29.24% id in 277 aa, and to Fluoribacter gormanii metallo-beta-lactamase Fez-1 protein blafez-1 SWALL:Q9K578 (EMBL:Y17896) (282 aa) fasta scores: E(): 7e-16, 29.04% id in 241 aa, and to Xanthomonas maltophilia metallo-beta-lactamase l1 precursor SWALL:BLA1_XANMA (SWALL:P52700) (290 aa) fasta scores: E(): 5.2e-14, 30.21% id in 235 aa. (342 aa)    
Predicted Functional Partners:
ECA2545
Similar to Yersinia pestis putative exported protein ypo1408 or y2762 SWALL:Q8ZG97 (EMBL:AJ414148) (182 aa) fasta scores: E(): 4.6e-60, 82.41% id in 182 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein ycbk or b0926 or c1068 or z1273 or ecs1009 or sf0923 SWALL:YCBK_ECOLI (SWALL:P75848) (182 aa) fasta scores: E(): 5.1e-56, 78.57% id in 182 aa.
  
    0.551
ECA2848
Similar to Yersinia pestis LysR-family transcriptional regulatory protein ypo0799 or y3187 SWALL:Q8ZHT5 (EMBL:AJ414144) (302 aa) fasta scores: E(): 1.6e-51, 45.81% id in 299 aa, and to Pseudomonas aeruginosa probable transcriptional regulator pa0056 SWALL:Q9I776 (EMBL:AE004445) (306 aa) fasta scores: E(): 2.2e-53, 46.33% id in 300 aa.
  
    0.550
galU
UTP--glucose-1-phosphate uridylyltransferase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri UTP--glucose-1-phosphate uridylyltransferase GalU or b1236 or c1700 or z2012 or ecs1738 or sf1236 SWALL:GALU_ECOLI (SWALL:P25520) (301 aa) fasta scores: E(): 4.5e-98, 85.08% id in 295 aa, and to Erwinia chrysanthemi GalU protein galU SWALL:Q93KA5 (EMBL:AJ410309) (303 aa) fasta scores: E(): 1.1e-106, 92.69% id in 301 aa.
      
 0.530
dhpS
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
     
 0.506
rne
Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
     
 0.472
galF
Similar to Escherichia coli, and Escherichia coli O157:H7 UTP--glucose-1-phosphate uridylyltransferase GalF or WcaN or b2042 or z3205 or ecs2846 SWALL:GALF_ECOLI (SWALL:P78083) (297 aa) fasta scores: E(): 7.1e-74, 65.43% id in 298 aa, and to Salmonella typhimurium, and Salmonella typhi UTP--glucose-1-phosphate uridylyltransferase GalF or stm2098 or sty2308 SWALL:GALF_SALTY (SWALL:P26390) (297 aa) fasta scores: E(): 7.1e-74, 64.43% id in 298 aa.
      
 0.467
clpB
ClpB protein (heat shock protein f84.1); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
      
 0.466
thiI
Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.460
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.449
rpoB
DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.440
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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