STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2876Similar to Xylella fastidiosa phage-related protein xf1763 SWALL:Q9PCL5 (EMBL:AE003998) (280 aa) fasta scores: E(): 7.8e-05, 26.69% id in 221 aa, and to Xanthomonas axonopodis phage-related protein orf84 or xac2285 SWALL:Q8PK90 (EMBL:AE011865) (320 aa) fasta scores: E(): 0.0092, 25.07% id in 327 aa. (279 aa)    
Predicted Functional Partners:
ECA2874
Similar to Fusobacterium nucleatum hypothetical protein Fn0445 SWALL:Q8RG72 (EMBL:AE010556) (292 aa) fasta scores: E(): 1.3e-13, 27.55% id in 294 aa.
 
     0.953
ECA2875
Putative ATP-binding protein; No significant database matches.
 
     0.953
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
 0.834
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
 
 0.776
nirE
Similar to Paracoccus denitrificans uroporphyrin-III C-methyltransferase NirE SWALL:NIRE_PARDE (SWALL:Q51701) (287 aa) fasta scores: E(): 2.3e-41, 49.6% id in 256 aa, and to Vibrio cholerae uroporphyrin-III C-methyltransferase vc2561 SWALL:Q9KP18 (EMBL:AE004324) (299 aa) fasta scores: E(): 1.6e-48, 58.15% id in 239 aa; Belongs to the precorrin methyltransferase family.
  
  
 0.748
cysG1
Siroheme synthase [includes: uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.748
cysG2
Siroheme synthase [includes: uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.748
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.639
sbp
Similar to Escherichia coli sulfate-binding protein precursor Sbp or b3917 SWALL:SUBI_ECOLI (SWALL:P06997) (329 aa) fasta scores: E(): 8e-77, 61.46% id in 327 aa.
  
  
 0.611
cysA
Sulphate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
  
  
 0.598
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.