STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2898Similar to Xanthomonas axonopodis plasmid mobilization protein MobL or xac3260 SWALL:Q8PHJ4 (EMBL:AE011971) (530 aa) fasta scores: E(): 4.1e-17, 32.84% id in 274 aa, and to Rhizobium loti probable conjugal transfer protein, TraA mll0964 SWALL:Q98LM6 (EMBL:AP002996) (1015 aa) fasta scores: E(): 1.6e-21, 36.1% id in 277 aa, and to Staphylococcus aureus orit nickase NeS neS SWALL:O87361 (EMBL:AF051917) (665 aa) fasta scores: E(): 2.4e-16, 33.99% id in 203 aa. (467 aa)    
Predicted Functional Partners:
recB
Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repai [...]
  
 
 0.773
recC
Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]
  
 
 0.732
dltB
Peptidoglycan biosynthesis protein; Similar to Bacillus subtilis protein DltB or ipa-4R SWALL:DLTB_BACSU (SWALL:P39580) (395 aa) fasta scores: E(): 3.9e-24, 31% id in 400 aa, and to Staphylococcus epidermidis DltB membrane protein se0625 SWALL:AAO04222 (EMBL:AE016746) (404 aa) fasta scores: E(): 1.1e-23, 28.9% id in 346 aa; Belongs to the membrane-bound acyltransferase family.
  
    0.621
ECA2180
Hypothetical protein; No significant database matches.
 
 
 0.600
ECA2899
Weakly similar to Sulfolobus tokodaii hypothetical protein St0486 SWALL:Q975C2 (EMBL:AP000982) (268 aa) fasta scores: E(): 0.37, 28.5% id in 214 aa, and to Fusobacterium nucleatum magnesium and cobalt transport protein cora fn0332 SWALL:Q8RGG6 (EMBL:AE010545) (351 aa) fasta scores: E(): 3.3, 25.09% id in 263 aa.
       0.550
dnaN
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
  
 
 0.506
ECA3160
Similar to Salmonella typhimurium putative transcriptional regulator stm2195 SWALL:Q8ZNL4 (EMBL:AE008798) (129 aa) fasta scores: E(): 3.8e-14, 38.68% id in 137 aa, and to Salmonella typhi putative DNA-binding protein sty2429 SWALL:Q8Z5A0 (EMBL:AL627273) (129 aa) fasta scores: E(): 4.4e-14, 38.68% id in 137 aa.
  
    0.501
ECA2819
Hypothetical protein; Weakly similar to Bacillus subtilis hypothetical protein YsfE SWALL:P94533 (EMBL:Z75208) (80 aa) fasta scores: E(): 0.92, 30% id in 60 aa.
  
    0.488
ECA2977
Similar to Pseudomonas fluorescens hypothetical protein SWALL:AAN32872 (EMBL:AF461725) (79 aa) fasta scores: E(): 1.6e-14, 59.42% id in 69 aa, and to Bradyrhizobium japonicum Blr3308 protein blr3308 SWALL:BAC48573 (EMBL:AP005947) (105 aa) fasta scores: E(): 0.04, 31.34% id in 67 aa.
  
     0.463
polA
Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.458
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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