STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA2911Putative DNA-binding protein; Similar to Corynebacterium efficiens putative transcription regulator ce1210 SWALL:BAC18020 (EMBL:AP005218) (378 aa) fasta scores: E(): 6.6e-43, 38.29% id in 376 aa, and to Neisseria meningitidis transcriptional regulator, hth_3 family nmb2012 SWALL:Q9JXJ6 (EMBL:AE002551) (363 aa) fasta scores: E(): 1.5e-30, 39.37% id in 353 aa. (370 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
 0.827
ECA2912
Putative plasmid-related protein; Similar to Brucella suis replication protein RepB bra1203 SWALL:Q8FUL8 (EMBL:AE014612) (328 aa) fasta scores: E(): 3.7, 24.3% id in 251 aa.
  
    0.827
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
 
 
 0.590
ECA2913
Putative DNA-binding protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri DNA-binding protein StpA or HnsB or b2669 or z3968 or ecs3530 or sf2697 SWALL:STPA_ECOLI (SWALL:P30017) (134 aa) fasta scores: E(): 0.0029, 42.18% id in 64 aa, and to Escherichia coli O6 hypothetical protein c2413 SWALL:Q8FGG4 (EMBL:AE016762) (80 aa) fasta scores: E(): 2.7e-18, 78.2% id in 78 aa.
       0.455
cas3
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Might be involved in the integration of spacer DNA into the CRISPR cassette. In the central section; belongs to the CRISPR-associated helicase Cas3 family.
 
     0.403
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.401
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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