Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA2932Similar to Ralstonia solanacearum putative drug efflux lipoprotein rsc3208 or rs02424 SWALL:Q8XUI0 (EMBL:AL646074) (486 aa) fasta scores: E(): 4e-119, 69.19% id in 487 aa, and to Xanthomonas campestris outer membrane protein oprn or xcc0419 SWALL:Q8PDC1 (EMBL:AE012139) (490 aa) fasta scores: E(): 9.1e-110, 65.09% id in 487 aa. (490 aa)    
Predicted Functional Partners:
ECA2930
HlyD-family secretion protein; Similar to Pseudomonas putida RND efflux membrane fusion protein pp3301 SWALL:AAN68908 (EMBL:AE016786) (367 aa) fasta scores: E(): 2.8e-81, 70.1% id in 368 aa, and to Xylella fastidiosa component of multidrug efflux system xf2084 SWALL:Q9PBQ6 (EMBL:AE004023) (368 aa) fasta scores: E(): 3.9e-75, 63.95% id in 369 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.894
ECA2931
Similar to Pseudomonas putida transcriptional regulator, TetR family pp3300 SWALL:AAN68907 (EMBL:AE016786) (204 aa) fasta scores: E(): 4.3e-53, 65.19% id in 204 aa, and to Xylella fastidiosa transcriptional regulator xf2085 SWALL:Q9PBQ5 (EMBL:AE004024) (205 aa) fasta scores: E(): 1.8e-50, 64.87% id in 205 aa.
 
   
 0.847
emrA
Similar to Erwinia chrysanthemi EmrA protein EmrA SWALL:Q93KB1 (EMBL:AJ410307) (391 aa) fasta scores: E(): 7.9e-104, 72.63% id in 391 aa, and to Escherichia coli multidrug resistance protein A EmrA or b2685 SWALL:EMRA_ECOLI (SWALL:P27303) (390 aa) fasta scores: E(): 5.7e-94, 68.28% id in 391 aa.
 
 0.833
ECA2929
Putative efflux protein; Similar to Pseudomonas putida rnd efflux transporter pp3302 SWALL:AAN68909 (EMBL:AE016786) (1030 aa) fasta scores: E(): 0, 84.11% id in 1020 aa, and to Xylella fastidiosa cation efflux system protein xf2083 SWALL:Q9PBQ7 (EMBL:AE004023) (1020 aa) fasta scores: E(): 0, 83.38% id in 1017 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.811
acrA
Acriflavine resistance protein A; Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein a precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECOLI (SWALL:P31223) (397 aa) fasta scores: E(): 4e-103, 72.29% id in 397 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.774
cusA
Similar to Escherichia coli putative cation efflux system protein CusA or b0575 SWALL:CUSA_ECOLI (SWALL:P38054) (1047 aa) fasta scores: E(): 0, 65.54% id in 1042 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.773
mexC
Multidrug resistance protein; Similar to Pseudomonas aeruginosa membrane fusion protein MexC or pa4599 SWALL:Q51395 (EMBL:U57969) (387 aa) fasta scores: E(): 6.2e-63, 50.78% id in 384 aa, and to uncultured bacterium MexC protein MexC SWALL:Q8RSM2 (EMBL:AJ431260) (388 aa) fasta scores: E(): 9.2e-63, 53.6% id in 375 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.773
acrB
Similar to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 0, 80.84% id in 1039 aa.
 0.765
mdtA
Similar to Salmonella typhimurium putative HlyD family secretion protein stm2126 SWALL:Q8ZNQ3 (EMBL:AE008794) (413 aa) fasta scores: E(): 1.9e-84, 63.27% id in 403 aa, and to Salmonella typhi putative efflux system protein sty2339 SWALL:Q8Z5F8 (EMBL:AL627273) (413 aa) fasta scores: E(): 2.2e-84, 63.27% id in 403 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.754
mexB
Similar to Pseudomonas aeruginosa multidrug resistance protein MexB or pa0426 SWALL:MEXB_PSEAE (SWALL:P52002) (1046 aa) fasta scores: E(): 1.9e-202, 50.82% id in 1037 aa, and to uncultured bacterium MexD protein mexD SWALL:Q8RSM1 (EMBL:AJ431260) (1047 aa) fasta scores: E(): 0, 64.14% id in 1043 aa.
 0.744
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.