STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2932Similar to Ralstonia solanacearum putative drug efflux lipoprotein rsc3208 or rs02424 SWALL:Q8XUI0 (EMBL:AL646074) (486 aa) fasta scores: E(): 4e-119, 69.19% id in 487 aa, and to Xanthomonas campestris outer membrane protein oprn or xcc0419 SWALL:Q8PDC1 (EMBL:AE012139) (490 aa) fasta scores: E(): 9.1e-110, 65.09% id in 487 aa. (490 aa)    
Predicted Functional Partners:
ECA2930
HlyD-family secretion protein; Similar to Pseudomonas putida RND efflux membrane fusion protein pp3301 SWALL:AAN68908 (EMBL:AE016786) (367 aa) fasta scores: E(): 2.8e-81, 70.1% id in 368 aa, and to Xylella fastidiosa component of multidrug efflux system xf2084 SWALL:Q9PBQ6 (EMBL:AE004023) (368 aa) fasta scores: E(): 3.9e-75, 63.95% id in 369 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.855
ECA2931
Similar to Pseudomonas putida transcriptional regulator, TetR family pp3300 SWALL:AAN68907 (EMBL:AE016786) (204 aa) fasta scores: E(): 4.3e-53, 65.19% id in 204 aa, and to Xylella fastidiosa transcriptional regulator xf2085 SWALL:Q9PBQ5 (EMBL:AE004024) (205 aa) fasta scores: E(): 1.8e-50, 64.87% id in 205 aa.
 
   
 0.847
emrA
Similar to Erwinia chrysanthemi EmrA protein EmrA SWALL:Q93KB1 (EMBL:AJ410307) (391 aa) fasta scores: E(): 7.9e-104, 72.63% id in 391 aa, and to Escherichia coli multidrug resistance protein A EmrA or b2685 SWALL:EMRA_ECOLI (SWALL:P27303) (390 aa) fasta scores: E(): 5.7e-94, 68.28% id in 391 aa.
 
 
 0.803
ECA2929
Putative efflux protein; Similar to Pseudomonas putida rnd efflux transporter pp3302 SWALL:AAN68909 (EMBL:AE016786) (1030 aa) fasta scores: E(): 0, 84.11% id in 1020 aa, and to Xylella fastidiosa cation efflux system protein xf2083 SWALL:Q9PBQ7 (EMBL:AE004023) (1020 aa) fasta scores: E(): 0, 83.38% id in 1017 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.773
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.755
ECA1386
Putative exported protein; Similar to Escherichia coli hypothetical protein CusX precursor CusX or b0573 SWALL:CUSX_ECOLI (SWALL:P77214) (110 aa) fasta scores: E(): 1.5e-06, 35.13% id in 111 aa, and to Shigella flexneri orf, conserved hypothetical protein ylcc or sf0474 SWALL:AAN42127 (EMBL:AE015079) (110 aa) fasta scores: E(): 1.5e-06, 35.13% id in 111 aa.
 
 
 0.691
acrA
Acriflavine resistance protein A; Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein a precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECOLI (SWALL:P31223) (397 aa) fasta scores: E(): 4e-103, 72.29% id in 397 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.688
mexC
Multidrug resistance protein; Similar to Pseudomonas aeruginosa membrane fusion protein MexC or pa4599 SWALL:Q51395 (EMBL:U57969) (387 aa) fasta scores: E(): 6.2e-63, 50.78% id in 384 aa, and to uncultured bacterium MexC protein MexC SWALL:Q8RSM2 (EMBL:AJ431260) (388 aa) fasta scores: E(): 9.2e-63, 53.6% id in 375 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.687
acrB
Similar to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 0, 80.84% id in 1039 aa.
 
 0.677
acrD
Similar to Escherichia coli probable aminoglycoside efflux pump AcrD or b2470 SWALL:ACRD_ECOLI (SWALL:P24177) (1037 aa) fasta scores: E(): 0, 79.51% id in 1035 aa, and to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 0, 64.87% id in 1042 aa.
 
 0.664
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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