STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifVHomocitrate synthase; Similar to Klebsiella pneumoniae homocitrate synthase NifV SWALL:NIFV_KLEPN (SWALL:P05345) (381 aa) fasta scores: E(): 1.8e-100, 68.94% id in 380 aa, and to Enterobacter agglomerans homocitrate synthase NifV SWALL:NIFV_ENTAG (SWALL:Q52070) (400 aa) fasta scores: E(): 1.6e-95, 68.4% id in 364 aa; Belongs to the alpha-IPM synthase/homocitrate synthase family. (391 aa)    
Predicted Functional Partners:
nahO
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.981
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.951
atoB
Similar to Clostridium acetobutylicum acetyl-CoA acetyltransferase ThlA or Thl or cac2873 SWALL:THLA_CLOAB (SWALL:P45359) (392 aa) fasta scores: E(): 9.5e-81, 59.48% id in 390 aa, and to Escherichia coli acetyl-CoA acetyltransferase AtoB or b2224 SWALL:ATOB_ECOLI (SWALL:P76461) (394 aa) fasta scores: E(): 1.2e-87, 64.01% id in 389 aa; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.928
adhE
Aldehyde-alcohol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase, acetaldehyde dehydrogenase, and pyruvate-formate-lyase deactivase AdhE or Ana or b1241 or z2016 or ecs1741 SWALL:ADHE_ECOLI (SWALL:P17547) (890 aa) fasta scores: E(): 0, 89.1% id in 890 aa; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.925
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
  
 
0.924
nifZ
Nitrogen fixation protein; Similar to Klebsiella pneumoniae NifZ protein NifZ SWALL:NIFZ_KLEPN (SWALL:P08533) (148 aa) fasta scores: E(): 3.6e-33, 57.24% id in 145 aa, and to Pantoea agglomerans NifZ protein NifZ SWALL:Q52072 (EMBL:X99694) (147 aa) fasta scores: E(): 5.6e-30, 56.55% id in 145 aa.
 
  
 0.923
nifJ
Similar to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_KLEPN (SWALL:P03833) (1171 aa) fasta scores: E(): 0, 78.27% id in 1169 aa, and to Enterobacter agglomerans pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_ENTAG (SWALL:P19543) (1173 aa) fasta scores: E(): 0, 73.34% id in 1178 aa. Also similar to ECA0824 (NifJ) (47.377% id. in 1182 aa overlap).
   
 
 0.909
aceB
Similar to Escherichia coli malate synthase A AceB or Mas or b4014 SWALL:MASY_ECOLI (SWALL:P08997) (533 aa) fasta scores: E(): 6.4e-180, 82.04% id in 529 aa.
   
 
 0.909
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.908
aceF
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.905
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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