STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2971Putative branched-chain amino acid aminotransferase; Similar to Listeria monocytogenes D-alanine aminotransferase Dat or DaaA or lmo1619 SWALL:DAAA_LISMO (SWALL:O85046) (289 aa) fasta scores: E(): 2.2e-24, 35.21% id in 284 aa, and to Methanopyrus kandleri branched-chain amino acid aminotransferase ilve or mk1627 SWALL:Q8TUX5 (EMBL:AE010451) (295 aa) fasta scores: E(): 6.5e-30, 34.05% id in 276 aa. (305 aa)    
Predicted Functional Partners:
ilvD
Similar to Escherichia coli dihydroxy-acid dehydratase IlvD or b3771 SWALL:ILVD_ECOLI (SWALL:P05791) (616 aa) fasta scores: E(): 9.7e-207, 87.98% id in 616 aa; Belongs to the IlvD/Edd family.
  
 0.970
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.959
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I [includes: aspartokinase I; homoserine dehydrogenase I] thra or thra1 or thra2 or b0002 SWALL:AK1H_ECOLI (SWALL:P00561) (820 aa) fasta scores: E(): 0, 82.41% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.920
metL
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase II MetL or MetM or b3940 SWALL:AK2H_ECOLI (SWALL:P00562) (809 aa) fasta scores: E(): 0, 83.12% id in 800 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.920
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.918
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.913
metB
Similar to Escherichia coli cystathionine gamma-synthase MetB or b3939 SWALL:METB_ECOLI (SWALL:P00935) (386 aa) fasta scores: E(): 3.8e-129, 87.01% id in 385 aa.
   
 0.912
avtA
Similar to Escherichia coli valine--pyruvate aminotransferase AvtA or b3572 SWALL:AVTA_ECOLI (SWALL:P09053) (417 aa) fasta scores: E(): 9.4e-133, 77.34% id in 415 aa.
     
 0.911
ECA3033
Probable aminotransferase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri probable aminotransferase yfbq or b2290 or c2831 or sf2366 SWALL:YFBQ_ECOLI (SWALL:P77727) (405 aa) fasta scores: E(): 1.8e-148, 89.6% id in 404 aa, and to Salmonella typhi putative aminotransferase t0533 SWALL:AAO68239 (EMBL:AE016836) (404 aa) fasta scores: E(): 2.3e-150, 91.58% id in 404 aa.
  
 
 0.908
gshA
Glutamate--cysteine ligase; Similar to Escherichia coli, and Escherichia coli O6 glutamate--cysteine ligase GshA or Gsh-I or b2688 or c3245 SWALL:GSH1_ECOLI (SWALL:P06980) (518 aa) fasta scores: E(): 1.3e-158, 73.15% id in 514 aa; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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