STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2987Similar to Escherichia coli hypothetical protein yehs or b2124 SWALL:YEHS_ECOLI (SWALL:P33355) (156 aa) fasta scores: E(): 1.4e-37, 62.82% id in 156 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yehs or stm2157 or sty2387 SWALL:Q8XEY4 (EMBL:AE008796) (155 aa) fasta scores: E(): 1e-36, 64% id in 150 aa. (154 aa)    
Predicted Functional Partners:
ECA1051
Similar to Yersinia pestis hypothetical protein Ypo1065 SWALL:Q8ZH46 (EMBL:AJ414146) (182 aa) fasta scores: E(): 2.4e-56, 75.28% id in 178 aa, and to Escherichia coli O6 hypothetical protein yaeq or c0229 SWALL:AAN78721 (EMBL:AE016755) (181 aa) fasta scores: E(): 6e-48, 62.22% id in 180 aa.
  
    0.630
ECA3671
Similar to Pseudomonas putida conserved hypothetical protein pp4958 SWALL:AAN70525 (EMBL:AE016792) (179 aa) fasta scores: E(): 4.7e-39, 59.25% id in 162 aa, and to Escherichia coli hypothetical protein ygjp or b3085 SWALL:YGJP_ECOLI (SWALL:P42597) (179 aa) fasta scores: E(): 2.5e-38, 61.14% id in 157 aa.
 
    0.565
mtnD1
Probable oxidase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
       0.547
rimO
Conserved hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
  
    0.506
queF
Putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
  
    0.500
rlmF
Conserved hypothetical protein; Specifically methylates the adenine in position 1618 of 23S rRNA.
  
     0.460
ECA2223
Similar to Streptomyces coelicolor putative TetR-family transcriptional regulatory protein sco4461 or scd65.04C SWALL:Q9F2S8 (EMBL:AL939120) (185 aa) fasta scores: E(): 3e-25, 42.68% id in 164 aa, and to Escherichia coli hypothetical protein ybjk or b0846 SWALL:YBJK_ECOLI (SWALL:P75811) (178 aa) fasta scores: E(): 5.6e-19, 38.69% id in 168 aa.
   
    0.456
parC
Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.439
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.438
lepB
Similar to Escherichia coli signal peptidase I LepB or b2568 SWALL:LEP_ECOLI (SWALL:P00803) (324 aa) fasta scores: E(): 4.7e-93, 69.75% id in 324 aa; Belongs to the peptidase S26 family.
   
    0.434
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.