Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fdhEFdhE protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (309 aa)    
Predicted Functional Partners:
fdnG
Similar to Escherichia coli formate dehydrogenase, nitrate-inducible, major subunit FdnG or b1474 SWALL:FDNG_ECOLI (SWALL:P24183) (1015 aa) fasta scores: E(): 0, 69.75% id in 1015 aa.
 
 
 0.942
fdnI
Formate dehydrogenase, nitrate-inducible, cytochrome b556; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri formate dehydrogenase, nitrate-inducible, cytochrome b556 FdnI or b1476 or z2234 or ecs2080 or sf1749 SWALL:FDNI_ECOLI (SWALL:P24185) (217 aa) fasta scores: E(): 7.5e-70, 78.19% id in 211 aa.
 
  
 0.936
fdnH
Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
 
  
 0.850
fdhD
Putative formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.638
modE
Putative molybdenum transport protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulator ModE or ModR or b0761 or z0931 or ecs0789 or sf0543 SWALL:MODE_ECOLI (SWALL:P46930) (262 aa) fasta scores: E(): 1.7e-60, 68.56% id in 264 aa.
 
   
 0.604
putA
Bifunctional PutA protein [includes: proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
      
 0.571
ECA2185
Putative membrane protein; Similar to Shigella flexneri orf, conserved hypothetical protein sf1208 SWALL:AAN42821 (EMBL:AE015147) (92 aa) fasta scores: E(): 5e-21, 57.14% id in 91 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein ychh or b1205 or c1663 or z1976 or ecs1710 SWALL:YCHH_ECOLI (SWALL:P31807) (92 aa) fasta scores: E(): 5.8e-21, 57.14% id in 91 aa.
  
     0.558
ECA0914
Putative component of polysulfide reductase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri NrfC protein precursor nrfc or b4072 or z5671 or ecs5054 or sf4132 SWALL:NRFC_ECOLI (SWALL:P32708) (223 aa) fasta scores: E(): 7.3e-49, 58.66% id in 225 aa. Also similar to ECA1877 (56.444% id. in 225 aa overlap).
 
  
 0.511
hybA
Hydrogenase-2 operon protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hydrogenase-2 operon protein hyba precursor HybA or b2996 or z4350 or ecs3881 or sf3043 SWALL:HYBA_ECOLI (SWALL:P37179) (328 aa) fasta scores: E(): 4.3e-93, 70.23% id in 336 aa.
 
  
 0.496
nrfC
Nitrite reductase complex component; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri NrfC protein precursor NrfC or b4072 or z5671 or ecs5054 or sf4132 SWALL:NRFC_ECOLI (SWALL:P32708) (223 aa) fasta scores: E(): 8.4e-76, 83.4% id in 223 aa. Also similar to ECA0914 (56.444% id. in 225 aa overlap).
 
  
 0.484
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.