Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECA3009Similar to Vibrio parahaemolyticus coproporphyrinogen oxidase homolog PhuW SWALL:Q9XCY7 (EMBL:AF119047) (420 aa) fasta scores: E(): 3.6e-47, 37.87% id in 396 aa, and to Yersinia pestis putative coproporphyrinogen III oxidase ypo0286 or y0547 SWALL:Q8ZJ42 (EMBL:AJ414141) (437 aa) fasta scores: E(): 2.2e-122, 69.1% id in 437 aa. (437 aa)    
Predicted Functional Partners:
ECA3008
Similar to Escherichia coli O6 hypothetical protein chux or c4315 SWALL:AAN82751 (EMBL:AE016768) (164 aa) fasta scores: E(): 1.6e-42, 65% id in 160 aa, and to Shigella dysenteriae hypothetical 18.4 kDa protein shuX SWALL:O70017 (EMBL:U64516) (164 aa) fasta scores: E(): 5.1e-41, 63.75% id in 160 aa.
   
 0.977
ECA3007
Conserved hypothetical protein; Similar to Escherichia coli O157:H7 orf, hypothetical protein chuy or z4917 or ecs4385 SWALL:Q8X5N4 (EMBL:AE005576) (207 aa) fasta scores: E(): 2.1e-40, 56.79% id in 206 aa, and to Shigella dysenteriae hypothetical 21.8 kDa protein shuY SWALL:O70016 (EMBL:U64516) (207 aa) fasta scores: E(): 4.4e-40, 57.28% id in 206 aa.
 
  
 0.828
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
 
  
 0.736
ompW
Outer membrane protein W; Similar to Escherichia coli, and Shigella flexneri outer membrane protein W precursor OmpW or b1256 or sf1259 SWALL:OMPW_ECOLI (SWALL:P21364) (212 aa) fasta scores: E(): 7.2e-54, 62.26% id in 212 aa.
  
  
 0.631
hemF
Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
    
 0.544
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
     
 0.519
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.513
hemG
Protoporphyrinogen oxidase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protoporphyrinogen oxidase HemG or b3850 or c4797 or z5372 or ecs4778 SWALL:HEMG_ECOLI (SWALL:P27863) (181 aa) fasta scores: E(): 8.5e-44, 62.14% id in 177 aa.
 
 
 0.503
ECA3632
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
0.447
ECA3006
Similar to Yersinia pestis putative membrane protein ypo1652 or y1815 SWALL:Q8ZFP2 (EMBL:AJ414149) (177 aa) fasta scores: E(): 4.5e-28, 47.74% id in 155 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein ylac or b0458 or z0570 or ecs0511 or sf0403 SWALL:AAN42059 (EMBL:AE000152) (169 aa) fasta scores: E(): 5.7e-20, 40.88% id in 159 aa.
       0.446
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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