STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3043Putative phosphoesterase; Similar to Salmonella typhimurium, and Salmonella typhi putative phosphoesterase yfce or stm2347 or sty2577 SWALL:Q8XGM7 (EMBL:AE008805) (183 aa) fasta scores: E(): 5.3e-49, 71.27% id in 181 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yfce or b2300 or c2843 or z3562 or ecs3184 SWALL:YFCE_ECOLI (SWALL:P76495) (184 aa) fasta scores: E(): 1.1e-50, 72.37% id in 181 aa. (183 aa)    
Predicted Functional Partners:
ECA3042
Similar to Yersinia pestis putative NUDIX hydrolase ypo2781 or y1614 SWALL:YR81_YERPE (SWALL:Q8ZD12) (182 aa) fasta scores: E(): 1.1e-56, 80.66% id in 181 aa, and to Salmonella typhimurium, and Salmonella typhi putative NUDIX hydrolase yfcd or stm2346 or sty2576 SWALL:YFCD_SALTY (SWALL:Q8XFF7) (184 aa) fasta scores: E(): 1.4e-55, 82.08% id in 173 aa.
  
    0.654
ECA3631
Ham1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.610
ECA2529
Putative phosphoesterase; Similar to Yersinia pestis hypothetical protein Ypo2037 SWALL:Q8ZEW6 (EMBL:AJ414151) (245 aa) fasta scores: E(): 1.1e-84, 84.89% id in 245 aa, and to Salmonella typhimurium, and Salmonella typhi putative histidinol phosphatase and related hydrolases of the php family ycdx or stm1136 or sty1173 SWALL:Q8XGW8 (EMBL:AE008749) (245 aa) fasta scores: E(): 1.8e-76, 75.1% id in 245 aa.
 
  
 0.491
ECA2715
Putative esterase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.452
ECA3044
Similar to Salmonella typhimurium putative glutathione S-transferase yfcg or stm2349 SWALL:Q8ZNC9 (EMBL:AE008805) (215 aa) fasta scores: E(): 2.4e-60, 71.98% id in 207 aa, and to Escherichia coli hypothetical GST-like protein yfcg or b2302 SWALL:YFCG_ECOLI (SWALL:P77526) (215 aa) fasta scores: E(): 5.7e-59, 71.01% id in 207 aa.
       0.442
rlmL
Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
     
 0.424
ECA3046
Similar to Yersinia pestis hypothetical protein Ypo2778 SWALL:Q8ZD15 (EMBL:AJ414153) (302 aa) fasta scores: E(): 1.1e-82, 71% id in 300 aa, and to Salmonella typhi hypothetical protein Sty2580 sty2580 SWALL:Q8Z512 (EMBL:AL627274) (297 aa) fasta scores: E(): 2.6e-78, 65.77% id in 298 aa.
       0.414
ECA1117
Probable peroxidase; Similar to Yersinia pestis putative alkyl hydroperoxide reductase subunit C AhpC or ypo3194 or y0988 SWALL:AAM84569 (EMBL:AJ414155) (200 aa) fasta scores: E(): 2.6e-76, 91.5% id in 200 aa, and to Vibrio vulnificus peroxiredoxin vv10453 SWALL:AAO08975 (EMBL:AE016798) (202 aa) fasta scores: E(): 1.4e-61, 73.5% id in 200 aa.
   
 
 0.405
ahpC
Alkyl hydroperoxide reductase C22 protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
   
 
 0.405
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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