Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA3046Similar to Yersinia pestis hypothetical protein Ypo2778 SWALL:Q8ZD15 (EMBL:AJ414153) (302 aa) fasta scores: E(): 1.1e-82, 71% id in 300 aa, and to Salmonella typhi hypothetical protein Sty2580 sty2580 SWALL:Q8Z512 (EMBL:AL627274) (297 aa) fasta scores: E(): 2.6e-78, 65.77% id in 298 aa. (301 aa)    
Predicted Functional Partners:
folX
D-erythro-7,8-dihydroneopterin triphosphate epimerase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri D-erythro-7,8-dihydroneopterin triphosphate epimerase FolX or b2303 or c2846 or z3565 or ecs3187 or sf2379 SWALL:FOLX_ECOLI (SWALL:P80449) (119 aa) fasta scores: E(): 1.1e-32, 77.39% id in 115 aa.
     
 0.774
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
  
 0.705
ECA2664
Conserved hypothetical protein; Similar to Yersinia pestis putative membrane protein ypo1356 or y2824 SWALL:Q8ZGE5 (EMBL:AJ414147) (496 aa) fasta scores: E(): 1.8e-130, 66.52% id in 475 aa, and to Escherichia coli hypothetical protein ybjt or b0869 SWALL:YBJT_ECOLI (SWALL:P75822) (476 aa) fasta scores: E(): 1.6e-119, 60.08% id in 471 aa.
    0.662
ECA3349
Similar to Yersinia pestis putative sigma 54 modulation protein ypo3279 SWALL:Q8ZBV5 (EMBL:AJ414156) (120 aa) fasta scores: E(): 3.7e-34, 84.95% id in 113 aa, and to Salmonella typhimurium, and Salmonella typhi ribosome associated factor, stabilizes ribosomes against dissociation yfia or stm2665 or sty2853 SWALL:Q8XEX6 (EMBL:AE008821) (112 aa) fasta scores: E(): 8.3e-31, 79.46% id in 112 aa.
   
    0.619
rne
Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
   
    0.588
blc
Outer membrane lipoprotein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.
      0.573
parC
Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.554
ECA2223
Similar to Streptomyces coelicolor putative TetR-family transcriptional regulatory protein sco4461 or scd65.04C SWALL:Q9F2S8 (EMBL:AL939120) (185 aa) fasta scores: E(): 3e-25, 42.68% id in 164 aa, and to Escherichia coli hypothetical protein ybjk or b0846 SWALL:YBJK_ECOLI (SWALL:P75811) (178 aa) fasta scores: E(): 5.6e-19, 38.69% id in 168 aa.
   
    0.554
lolB
Outer-membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
   
    0.551
ECA1051
Similar to Yersinia pestis hypothetical protein Ypo1065 SWALL:Q8ZH46 (EMBL:AJ414146) (182 aa) fasta scores: E(): 2.4e-56, 75.28% id in 178 aa, and to Escherichia coli O6 hypothetical protein yaeq or c0229 SWALL:AAN78721 (EMBL:AE016755) (181 aa) fasta scores: E(): 6e-48, 62.22% id in 180 aa.
   
    0.549
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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