STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flkCell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system. (417 aa)    
Predicted Functional Partners:
wecH
Putative membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
     0.766
aaeX
Putative membrane protein; Similar to Serratia marcescens hypothetical 7.8 kDa protein yhcR SWALL:Q8RQS4 (EMBL:AB080601) (67 aa) fasta scores: E(): 3.5e-20, 80.64% id in 62 aa, and to Yersinia pestis putative membrane protein ypo3684 or y0179 SWALL:Q8ZAV0 (EMBL:AJ414158) (67 aa) fasta scores: E(): 5.7e-20, 76.56% id in 64 aa.
  
     0.756
sseB
Enhanced serine sensitivity protein; Similar to Escherichia coli, and Shigella flexneri protein SseB or b2522 or sf2569 SWALL:SSEB_ECOLI (SWALL:P31143) (258 aa) fasta scores: E(): 1.6e-51, 55.11% id in 254 aa.
  
     0.753
ECA0086
Similar to Yersinia pestis putative exported protein ypo4070 SWALL:Q8Z9W8 (EMBL:AJ414160) (241 aa) fasta scores: E(): 1.3e-39, 49.11% id in 226 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YiaF SWALL:AAN45039 (EMBL:U00039) (276 aa) fasta scores: E(): 2.7e-33, 44.09% id in 220 aa.
  
     0.743
ECA1841
Similar to Escherichia coli hypothetical protein ydiv or b1707 SWALL:YDIV_ECOLI (SWALL:P76204) (237 aa) fasta scores: E(): 3.5e-23, 36.17% id in 235 aa, and to Shigella flexneri orf, conserved hypothetical protein ydiv or sf1524 SWALL:AAN43114 (EMBL:AE015175) (237 aa) fasta scores: E(): 3.1e-22, 35.74% id in 235 aa.
  
     0.742
ECA2253
Putative exported protein; Similar to Yersinia pseudotuberculosis hypothetical 14.2 kDa protein orf9 SWALL:Q93AP0 (EMBL:AF418982) (124 aa) fasta scores: E(): 8.4e-19, 45.52% id in 123 aa, and to Salmonella typhimurium, and Salmonella typhi putative periplasmic protein ynfb or stm1503 or sty1560 SWALL:Q8XEU2 (EMBL:AE008765) (113 aa) fasta scores: E(): 3.1e-18, 52.52% id in 99 aa; Belongs to the UPF0482 family.
  
     0.737
yfeE
Putative membrane protein; Similar to Yersinia pestis putative yfeabcd regulator YfeE or ypo2445 or y1891 SWALL:YFEE_YERPE (SWALL:Q56956) (184 aa) fasta scores: E(): 1.8e-48, 63.73% id in 182 aa, and to Salmonella typhimurium, and Salmonella typhi putative regulator ynib or stm1323 or sty1788 SWALL:Q8XFB7 (EMBL:AE008757) (178 aa) fasta scores: E(): 6.8e-47, 63.33% id in 180 aa.
  
     0.735
ompX
Outer membrane protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri outer membrane protein X precursor OmpX or b0814 or c0900 or z1036 or ecs0892 or sf0765 SWALL:OMPX_ECOLI (SWALL:P36546) (171 aa) fasta scores: E(): 9.1e-40, 66.47% id in 173 aa.
  
     0.733
mzrA
Putative exported protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
     0.726
ampE
Putative membrane-bound sensory transducer; Similar to Escherichia coli, and Shigella flexneri AmpE protein AmpE or b0111 or sf0108 SWALL:AMPE_ECOLI (SWALL:P13017) (284 aa) fasta scores: E(): 6.6e-77, 66.19% id in 284 aa.
  
     0.725
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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