STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mepAPenicillin-insensitive murein endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. (281 aa)    
Predicted Functional Partners:
ECA3067
Similar to Yersinia pestis putative membrane protein ypo2753 or y1587 SWALL:Q8ZD39 (EMBL:AJ414153) (268 aa) fasta scores: E(): 2e-74, 73.48% id in 264 aa, and to Salmonella typhimurium, and Salmonella typhi putative permease yfca or stm2382 or sty2614 SWALL:Q8XEQ5 (EMBL:AE008807) (269 aa) fasta scores: E(): 5.2e-72, 71.37% id in 262 aa.
 
    0.934
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
  
 0.820
ECA2545
Similar to Yersinia pestis putative exported protein ypo1408 or y2762 SWALL:Q8ZG97 (EMBL:AJ414148) (182 aa) fasta scores: E(): 4.6e-60, 82.41% id in 182 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein ycbk or b0926 or c1068 or z1273 or ecs1009 or sf0923 SWALL:YCBK_ECOLI (SWALL:P75848) (182 aa) fasta scores: E(): 5.1e-56, 78.57% id in 182 aa.
  
   
 0.739
ECA3066
Conserved hypothetical protein; Similar to Salmonella typhimurium putative cytoplasmic protein yfcm or stm2381 SWALL:Q8ZNB1 (EMBL:AE008807) (182 aa) fasta scores: E(): 5.4e-64, 77.9% id in 181 aa, and to Shigella flexneri putative transporting ATPase yfcm or sf2402 SWALL:AAN43915 (EMBL:AE015256) (182 aa) fasta scores: E(): 6.4e-64, 77.9% id in 181 aa.
       0.724
ECA3065
Similar to Yersinia pestis hypothetical protein Ypo2755 SWALL:Q8ZD37 (EMBL:AJ414153) (92 aa) fasta scores: E(): 6.4e-25, 75% id in 92 aa, and to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein yfcl or b2325 or z3588 or ecs3209 SWALL:YFCL_ECOLI (SWALL:P76496) (92 aa) fasta scores: E(): 1.3e-20, 67.41% id in 89 aa.
       0.642
ECA1987
Putative membrane protein; Similar to Escherichia coli, and Escherichia coli O6 hypothetical protein ycjf or b1322 or c1794 SWALL:YCJF_ECOLI (SWALL:P45525) (353 aa) fasta scores: E(): 1.2e-102, 75.28% id in 348 aa, and to Shigella flexneri orf, conserved hypothetical protein ycjf or sf1328 SWALL:AAN42934 (EMBL:AE015159) (353 aa) fasta scores: E(): 1.5e-102, 75% id in 348 aa.
  
     0.632
ECA1986
Conserved hypothetical protein; Similar to Yersinia enterocolitica hypothetical 52.6 kDa protein ycjX SWALL:Q9F4H0 (EMBL:AY008264) (465 aa) fasta scores: E(): 4.4e-166, 81.93% id in 465 aa, and to Escherichia coli hypothetical protein ycjx or b1321 SWALL:YCJX_ECOLI (SWALL:P76046) (465 aa) fasta scores: E(): 1.1e-154, 76.34% id in 465 aa.
  
     0.620
prmB
Conserved hypothetical protein; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
       0.602
pldB
Lysophospholipase L2; Similar to Escherichia coli lysophospholipase L2 PldB or b3825 SWALL:PLDB_ECOLI (SWALL:P07000) (340 aa) fasta scores: E(): 3e-78, 59.56% id in 324 aa.
  
     0.564
creA
Putative exported protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri crea protein CreA or b4397 or c5484 or z6000 or ecs5355 or sf4429 SWALL:CREA_ECOLI (SWALL:P08367) (157 aa) fasta scores: E(): 3e-45, 78.8% id in 151 aa, and to Yersinia pestis putative exported protein ypo0457 or CreA or y3722 SWALL:Q8ZIN8 (EMBL:AJ414142) (155 aa) fasta scores: E(): 6.9e-47, 84.93% id in 146 aa.
  
     0.486
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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