STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa)    
Predicted Functional Partners:
tyrA
Similar to Escherichia coli T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA or b2600 SWALL:TYRA_ECOLI (SWALL:P07023) (373 aa) fasta scores: E(): 1.6e-123, 87.13% id in 373 aa.
 
 0.996
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.995
trpG
Similar to Serratia marcescens anthranilate synthase component II TrpG SWALL:TRPG_SERMA (SWALL:P00900) (192 aa) fasta scores: E(): 6.3e-60, 85.34% id in 191 aa, and to Yersinia pestis anthranilate synthase component II TrpG or ypo2207 or y2050.1 SWALL:Q8ZEG6 (EMBL:AJ414151) (192 aa) fasta scores: E(): 5.4e-62, 84.89% id in 192 aa.
 
 
 0.988
pheA
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri P-protein [includes: chorismate mutase and prephenate dehydratase] PheA or b2599 or z3891 or ecs3462 or sf2659 SWALL:PHEA_ECOLI (SWALL:P07022) (386 aa) fasta scores: E(): 1e-115, 76.17% id in 382 aa.
 
 
 0.981
trpE
Similar to Escherichia coli anthranilate synthase component I TrpE or b1264 SWALL:TRPE_ECOLI (SWALL:P00895) (520 aa) fasta scores: E(): 2.8e-154, 77.5% id in 520 aa.
 
 
 0.969
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
  
 0.961
ECA1449
Putative chorismate mutase; Similar to Erwinia herbicola monofunctional chorismate mutase precursor AroQ SWALL:CHMU_ERWHE (SWALL:P42517) (181 aa) fasta scores: E(): 1.2e-18, 38.88% id in 180 aa, and to Yersinia pestis putative chorismate mutase ypo1353 or y2828 SWALL:Q8ZGE8 (EMBL:AJ414147) (186 aa) fasta scores: E(): 5.3e-17, 34.83% id in 178 aa.
  
 
 0.959
pabB
Similar to Escherichia coli para-aminobenzoate synthase component I PabB or b1812 SWALL:PABB_ECOLI (SWALL:P05041) (453 aa) fasta scores: E(): 6.5e-119, 66.51% id in 433 aa.
 
 
 0.943
ECA4066
Para-aminobenzoate synthase, glutamine amidotransferase component II.
 
 
 0.932
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 0.930
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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