Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
ECA3071Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yfcn or b2331 or c2877 or sf2406 SWALL:YFCN_ECOLI (SWALL:P77458) (183 aa) fasta scores: E(): 2.2e-54, 73.71% id in 175 aa, and to Salmonella typhimurium, and Salmonella typhi hypothetical protein yfcn or stm2386 or sty2618 SWALL:YFCN_SALTY (SWALL:Q8XFE8) (183 aa) fasta scores: E(): 3e-54, 73.14% id in 175 aa; Belongs to the UPF0115 family. (180 aa)    
Predicted Functional Partners:
rplY
50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.
  
 
   0.718
rplD
50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
   0.705
rpsU
30S ribosomal subunit protein S21; Identical to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, Shigella flexneri, and Yersinia pestis 30S ribosomal protein S21 RpsU or b3065 or c3816 or z4418 or ecs3948 or stm3209 or sty3388 or t3129 or sf3106 or ypo0645 or y3535 SWALL:RS21_ECOLI (SWALL:P02379) (70 aa) fasta scores: E(): 2.7e-24, 100% id in 70 aa; Belongs to the bacterial ribosomal protein bS21 family.
  
 
   0.692
rpsJ
30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
 
 0.663
rpsL
30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.
   
   0.662
rpsG
30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.660
metJ
Repressor of the methionine regulon; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
     0.651
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
   
   0.648
rpmB
50S ribosomal protein L28; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 50S ribosomal protein L28 RpmB or b3637 or c4461 or z5061 or ecs4512 or sf3676 SWALL:RL28_ECOLI (SWALL:P02428) (77 aa) fasta scores: E(): 3.3e-29, 93.5% id in 77 aa; Belongs to the bacterial ribosomal protein bL28 family.
    
   0.643
rpmG
50S ribosomal protein L33; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri 50S ribosomal protein L33 SWALL:RL33_ECOLI (SWALL:P02436) (54 aa) fasta scores: E(): 1.6e-19, 96.29% id in 54 aa; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.643
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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