STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsdMSubunit M of type I restriction-modification system; Similar to Escherichia coli type I restriction enzyme EcoEI M protein HsdM SWALL:T1ME_ECOLI (SWALL:Q47282) (490 aa) fasta scores: E(): 6.2e-193, 97.55% id in 490 aa, and to Salmonella enterica styski methylase HsdM SWALL:P95732 (EMBL:Y11005) (493 aa) fasta scores: E(): 2e-178, 89.38% id in 490 aa. (490 aa)    
Predicted Functional Partners:
hsdS
Subunit S of type I restriction-modification system; Similar to Escherichia coli type i restriction enzyme EcoEI specificity protein HsdS or Hss SWALL:T1SE_ECOLI (SWALL:P19705) (594 aa) fasta scores: E(): 4.7e-62, 44.05% id in 606 aa, and to Salmonella enterica styski methylase HsdS SWALL:P95733 (EMBL:Y11005) (587 aa) fasta scores: E(): 6.2e-57, 40.95% id in 608 aa.
 
 
 0.996
hsdR
Similar to Escherichia coli type I restriction enzyme EcoEI R protein HsdR or Hsr SWALL:T1RE_ECOLI (SWALL:Q47281) (813 aa) fasta scores: E(): 0, 94.71% id in 813 aa, and to Pseudomonas putida type I restriction-modification system, R subunit hsdr or pp4740 SWALL:AAN70312 (EMBL:AE016791) (787 aa) fasta scores: E(): 3.5e-149, 61.76% id in 803 aa.
 
   
 0.909
NucS
Hypothetical protein; No significant database matches.
 
    0.866
ECA0584
Similar to Bacillus coagulans restriction enzyme bgci alpha subunit bcgiA SWALL:T4BA_BACCO (SWALL:Q07605) (637 aa) fasta scores: E(): 1.3e-46, 31.12% id in 633 aa, and to Staphylococcus aureus bacteriophage phi-42 hypothetical 72.6 kDa protein SWALL:P95687 (EMBL:X94423) (639 aa) fasta scores: E(): 1.9e-42, 30.78% id in 653 aa.
  
     0.725
ECA2660
Similar to Yersinia pestis hypothetical protein Ypo1362 ypo1362 SWALL:Q8ZGD9 (EMBL:AJ414148) (555 aa) fasta scores: E(): 1.1e-152, 66.3% id in 555 aa, and to Escherichia coli hypothetical protein ybjd or b0876 SWALL:YBJD_ECOLI (SWALL:P75828) (552 aa) fasta scores: E(): 1.3e-148, 67.14% id in 554 aa.
  
  
 0.618
ruvC
Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
      
 0.557
lhr
Similar to Escherichia coli probable ATP-dependent helicase Lhr or RhlF or b1653 SWALL:LHR_ECOLI (SWALL:P30015) (1538 aa) fasta scores: E(): 9.6e-156, 57.39% id in 1603 aa, and to Streptomyces coelicolor ATP dependent DNA helicase sco5761 or sc7c7.16C SWALL:O86821 (EMBL:AL939125) (1690 aa) fasta scores: E(): 3.8e-129, 51.11% id in 1479 aa.
  
  
 0.438
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.