STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsdRSimilar to Escherichia coli type I restriction enzyme EcoEI R protein HsdR or Hsr SWALL:T1RE_ECOLI (SWALL:Q47281) (813 aa) fasta scores: E(): 0, 94.71% id in 813 aa, and to Pseudomonas putida type I restriction-modification system, R subunit hsdr or pp4740 SWALL:AAN70312 (EMBL:AE016791) (787 aa) fasta scores: E(): 3.5e-149, 61.76% id in 803 aa. (808 aa)    
Predicted Functional Partners:
hsdS
Subunit S of type I restriction-modification system; Similar to Escherichia coli type i restriction enzyme EcoEI specificity protein HsdS or Hss SWALL:T1SE_ECOLI (SWALL:P19705) (594 aa) fasta scores: E(): 4.7e-62, 44.05% id in 606 aa, and to Salmonella enterica styski methylase HsdS SWALL:P95733 (EMBL:Y11005) (587 aa) fasta scores: E(): 6.2e-57, 40.95% id in 608 aa.
 
  
 0.910
hsdM
Subunit M of type I restriction-modification system; Similar to Escherichia coli type I restriction enzyme EcoEI M protein HsdM SWALL:T1ME_ECOLI (SWALL:Q47282) (490 aa) fasta scores: E(): 6.2e-193, 97.55% id in 490 aa, and to Salmonella enterica styski methylase HsdM SWALL:P95732 (EMBL:Y11005) (493 aa) fasta scores: E(): 2e-178, 89.38% id in 490 aa.
 
   
 0.909
rpoB
DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.908
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.900
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.900
ECA2375
Similar to Yersinia pestis putative dead box family helicase ypo2071 or y2239 SWALL:Q8ZET2 (EMBL:AJ414151) (634 aa) fasta scores: E(): 2.8e-217, 84.12% id in 630 aa, and to Escherichia coli O6 probable ATP-dependent helicase yoaa c2212 SWALL:AAN80671 (EMBL:AE016761) (636 aa) fasta scores: E(): 1.2e-208, 80.57% id in 628 aa.
   
 0.810
dinG
Probable ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase.
   
 0.810
hepA
RNA polymerase associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
 
 
 0.802
rpoC
DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.732
ECA0584
Similar to Bacillus coagulans restriction enzyme bgci alpha subunit bcgiA SWALL:T4BA_BACCO (SWALL:Q07605) (637 aa) fasta scores: E(): 1.3e-46, 31.12% id in 633 aa, and to Staphylococcus aureus bacteriophage phi-42 hypothetical 72.6 kDa protein SWALL:P95687 (EMBL:X94423) (639 aa) fasta scores: E(): 1.9e-42, 30.78% id in 653 aa.
 
   
 0.718
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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