STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ugdSimilar to Escherichia coli UDP-glucose 6-dehydrogenase Ugd or b2028 SWALL:UDG_ECOLI (SWALL:P76373) (388 aa) fasta scores: E(): 2.4e-110, 73.96% id in 388 aa, and to Vibrio cholerae nucleotide sugar dehydrogenase SWALL:Q56625 (EMBL:U47057) (388 aa) fasta scores: E(): 1e-110, 72.93% id in 388 aa. (388 aa)    
Predicted Functional Partners:
arnA
Probable formyl transferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
 
 0.987
galF
Similar to Escherichia coli, and Escherichia coli O157:H7 UTP--glucose-1-phosphate uridylyltransferase GalF or WcaN or b2042 or z3205 or ecs2846 SWALL:GALF_ECOLI (SWALL:P78083) (297 aa) fasta scores: E(): 7.1e-74, 65.43% id in 298 aa, and to Salmonella typhimurium, and Salmonella typhi UTP--glucose-1-phosphate uridylyltransferase GalF or stm2098 or sty2308 SWALL:GALF_SALTY (SWALL:P26390) (297 aa) fasta scores: E(): 7.1e-74, 64.43% id in 298 aa.
  
 0.954
galU
UTP--glucose-1-phosphate uridylyltransferase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri UTP--glucose-1-phosphate uridylyltransferase GalU or b1236 or c1700 or z2012 or ecs1738 or sf1236 SWALL:GALU_ECOLI (SWALL:P25520) (301 aa) fasta scores: E(): 4.5e-98, 85.08% id in 295 aa, and to Erwinia chrysanthemi GalU protein galU SWALL:Q93KA5 (EMBL:AJ410309) (303 aa) fasta scores: E(): 1.1e-106, 92.69% id in 301 aa.
  
 0.954
ECA1430
Similar to Cicer arietinum dTDP-glucose 4-6-dehydratase SWALL:Q9SMJ5 (EMBL:AJ275318) (346 aa) fasta scores: E(): 1.7e-10, 28.52% id in 284 aa, and to Leptospira interrogans dTDP-glucose 4,6-dehydratase RfbB4 or la1661 SWALL:AAN48860 (EMBL:AE011344) (369 aa) fasta scores: E(): 1.2e-09, 28.67% id in 279 aa.
 
 0.953
galE
Similar to Escherichia coli udp-glucose 4-epimerase GalE or GalD or b0759 SWALL:GALE_ECOLI (SWALL:P09147) (338 aa) fasta scores: E(): 5.5e-102, 76.03% id in 338 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
 
 0.947
rfbC
dTDP-6-deoxy-D-glucose-3,5 epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.932
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
  
 0.932
rffG
Similar to Escherichia coli dTDP-glucose 4,6-dehydratase RffG or b3788 SWALL:RFFG_ECOLI (SWALL:P27830) (355 aa) fasta scores: E(): 6.4e-119, 83% id in 353 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
  
 0.878
galT
Similar to Escherichia coli galactose-1-phosphate uridylyltransferase GalT or GalB or b0758 SWALL:GAL7_ECOLI (SWALL:P09148) (348 aa) fasta scores: E(): 9.5e-111, 74.92% id in 343 aa.
    
 0.816
wzxE
Enterobacterial common antigen (ECA) biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
  
  
 0.760
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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