STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (690 aa)    
Predicted Functional Partners:
ppx
Exopolyphosphatase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 exopolyphosphatase Ppx or b2502 or c3020 or z3765 or ecs3364 SWALL:PPX_ECOLI (SWALL:P29014) (512 aa) fasta scores: E(): 8.4e-153, 75.3% id in 498 aa; Belongs to the GppA/Ppx family.
 
  
 0.950
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.930
gppA
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
 
  
 0.794
pstA
Phosphate ABC transporter permease protein; Similar to Pseudomonas aeruginosa a transmembrane component of the phosphate specific transport complex PstA SWALL:Q51545 (EMBL:D45195) (513 aa) fasta scores: E(): 8.4e-82, 50.99% id in 502 aa, and to Yersinia pestis putative phosphate transport system permease PstA or ypo2834 SWALL:Q8ZCX4 (EMBL:AJ414153) (570 aa) fasta scores: E(): 3.2e-124, 65.88% id in 551 aa.
     
 0.714
ECA2796
Hypothetical protein; No significant database matches.
  
  
 0.609
pstB
Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.590
polA
Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.548
pstC
Similar to Pseudomonas aeruginosa phosphate transport system permease protein PstC or pa5368 SWALL:Q51544 (EMBL:D45195) (677 aa) fasta scores: E(): 4e-85, 40.05% id in 674 aa, and to Yersinia pestis putative phosphate transport system permease PstC or ypo2835 or y1399 SWALL:Q8ZCX3 (EMBL:AJ414153) (749 aa) fasta scores: E(): 1.2e-107, 52.21% id in 745 aa.
       0.546
ECA3166
Hypothetical protein; No significant database matches.
       0.427
pitA
Low-affinity inorganic phosphate transporter; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 low-affinity inorganic phosphate transporter 1 PitA or Pit or b3493 or c4291 or z4893 or ecs4365 SWALL:PITA_ECOLI (SWALL:P37308) (499 aa) fasta scores: E(): 1.3e-136, 70.37% id in 503 aa.
     
 0.414
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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