STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3199Putative membrane protein; Similar to Yersinia pestis HmsT or ypo0425 or y3756 SWALL:AAM87301 (EMBL:AF129277) (390 aa) fasta scores: E(): 1.1e-12, 28.21% id in 319 aa, and to Pseudomonas putida GGDEF domain protein pp3452 SWALL:AAN69054 (EMBL:AE016786) (363 aa) fasta scores: E(): 2.2e-12, 32.65% id in 245 aa. (307 aa)    
Predicted Functional Partners:
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
 
 0.970
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
 
 0.962
ECA3270
Putative exported protein; Similar to Rhizobium meliloti hypothetical protein r00959 or smc00038 SWALL:Q92KJ3 (EMBL:AL591785) (772 aa) fasta scores: E(): 1e-48, 35.35% id in 461 aa, and to Xanthomonas campestris c-di-gmp phosphodiesterase A PdeA or xcc1865 SWALL:Q8P9J8 (EMBL:AE012289) (726 aa) fasta scores: E(): 1.1e-41, 31.81% id in 462 aa.
 
  
 0.932
ECA2008
Putative signaling protein; Similar to Pseudomonas aeruginosa hypothetical protein Pa2567 SWALL:Q9I0R8 (EMBL:AE004685) (587 aa) fasta scores: E(): 1.7e-61, 32.99% id in 582 aa, and to Xanthomonas campestris hypothetical protein Xcc1777 SWALL:Q8P9S1 (EMBL:AE012279) (618 aa) fasta scores: E(): 2e-57, 32.88% id in 590 aa.
 
 
 0.929
ECA3549
Putative signaling protein; Similar to Vibrio vulnificus response regulator VieA vv21511 SWALL:AAO08375 (EMBL:AE016813) (386 aa) fasta scores: E(): 5.5e-16, 30.04% id in 233 aa, and to Anabaena sp. two-component response regulator alr1230 SWALL:Q8YXI3 (EMBL:AP003585) (403 aa) fasta scores: E(): 7.6e-16, 30.35% id in 224 aa.
 
 
 0.927
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
 
 0.905
ECA3271
Similar to Yersinia pestis hypothetical protein Ypo3988 SWALL:Q8ZA32 (EMBL:AJ414160) (276 aa) fasta scores: E(): 1.6e-49, 51.48% id in 235 aa, and to Escherichia coli O157:H7 orf, hypothetical protein yhjh or z4939 or ecs4405 SWALL:Q8X5M5 (EMBL:AE005578) (255 aa) fasta scores: E(): 5.4e-46, 50.63% id in 237 aa.
 
 
 
 0.867
rcsC
Two-component system sensor protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
 
 0.815
ECA1081
Probable transcriptional regulator; Similar to Escherichia coli O6 hypothetical protein ylab or c0575 SWALL:AAN79053 (EMBL:AE016756) (518 aa) fasta scores: E(): 1.1e-54, 35.17% id in 506 aa, and to Shigella flexneri orf, conserved hypothetical protein sf0402 SWALL:AAN42058 (EMBL:AE015072) (518 aa) fasta scores: E(): 3.2e-53, 34.58% id in 506 aa.
 
     0.772
ECA0046
Putative signaling membrane protein; Similar to Escherichia coli Rtn protein or b2176 SWALL:RTN_ECOLI (SWALL:P76446) (518 aa) fasta scores: E(): 6.1e-42, 30.6% id in 513 aa, and to Salmonella typhi putative Rtn protein sty0376 SWALL:Q8Z923 (EMBL:AL627266) (524 aa) fasta scores: E(): 1.8e-67, 35.68% id in 524 aa. In E.coli it's found to be involved in resistance to phages N4 and lambda.
 
     0.770
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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