STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3222Conserved hypothetical protein; Similar to Pseudomonas aeruginosa PilF protein SWALL:Q51526 (EMBL:L49434) (198 aa) fasta scores: E(): 4.5e-07, 28.4% id in 169 aa, and to Yersinia pestis putative fimbrial biogenesis protein ypo2881 or y1351 SWALL:Q8ZCT4 (EMBL:AJ414154) (249 aa) fasta scores: E(): 4.2e-62, 71.91% id in 235 aa. (245 aa)    
Predicted Functional Partners:
rodZ
Putative DNA-binding protein; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
  
    0.836
ispG
1-hydroxy-2-methyl-2-(e)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
    0.713
ECA3808
Similar to Yersinia pestis hypothetical protein ypo0562 or y3619 SWALL:Q8ZIE2 (EMBL:AJ414143) (176 aa) fasta scores: E(): 4.8e-42, 67.81% id in 174 aa, and to Vibrio cholerae hypothetical protein Vc2395 SWALL:Q9KPH3 (EMBL:AE004310) (157 aa) fasta scores: E(): 3.3e-11, 33.74% id in 163 aa.
  
    0.698
ECA3218
Similar to Yersinia pestis putative membrane protein ypo2877 or y1355 SWALL:Q8ZCT7 (EMBL:AJ414154) (211 aa) fasta scores: E(): 3.2e-42, 61.13% id in 211 aa, and to Escherichia coli O6 hypothetical protein yfgm or c3035 SWALL:AAN81485 (EMBL:AE016764) (206 aa) fasta scores: E(): 1.8e-40, 57.56% id in 205 aa.
 
     0.684
ECA0687
Putative DNA-binding protein; Similar to Yersinia pestis hypothetical protein ypo3514 SWALL:AAM84258 (EMBL:AJ414157) (133 aa) fasta scores: E(): 1.9e-17, 47.32% id in 112 aa and to bacteriophage D3112 transposase A SWALL:Q38013 (EMBL:X87627) (690 aa) fasta scores: E(): 0.00026, 33.69% id in 92 aa.
  
     0.664
bamB
Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
     0.587
polA
Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.576
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
    0.564
ECA4098
Similar to Yersinia pestis hypothetical protein ypo0146 or y3925 SWALL:Q8ZJG2 (EMBL:AJ414141) (313 aa) fasta scores: E(): 7.5e-48, 45.54% id in 292 aa, and to Salmonella typhi hypothetical protein yrfd or t4014 SWALL:AAO71484 (EMBL:AE016847) (259 aa) fasta scores: E(): 8.5e-14, 29.74% id in 279 aa.
 
   
 0.563
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.558
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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