| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA3231 | fdx | ECA3231 | ECA3232 | Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yfhj or b2524 or z3791 or ecs3390 or sf2571 SWALL:AAN44070 (EMBL:M88654) (66 aa) fasta scores: E(): 3.5e-23, 83.33% id in 66 aa, and to Yersinia pestis hypothetical protein ypo2890 or y1341 SWALL:Q8ZCS7 (EMBL:AJ414154) (66 aa) fasta scores: E(): 6.1e-20, 76.56% id in 64 aa. | Ferredoxin, 2Fe-2S; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ferredoxin, 2fe-2s Fdx or b2525 or z3792 or ecs3391 or sf2572 SWALL:AAN44071 (EMBL:M88654) (111 aa) fasta scores: E(): 6.7e-39, 84.68% id in 111 aa. | 0.998 |
| ECA3231 | hscA | ECA3231 | ECA3233 | Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yfhj or b2524 or z3791 or ecs3390 or sf2571 SWALL:AAN44070 (EMBL:M88654) (66 aa) fasta scores: E(): 3.5e-23, 83.33% id in 66 aa, and to Yersinia pestis hypothetical protein ypo2890 or y1341 SWALL:Q8ZCS7 (EMBL:AJ414154) (66 aa) fasta scores: E(): 6.1e-20, 76.56% id in 64 aa. | Chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.970 |
| ECA3231 | hscB | ECA3231 | ECA3234 | Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yfhj or b2524 or z3791 or ecs3390 or sf2571 SWALL:AAN44070 (EMBL:M88654) (66 aa) fasta scores: E(): 3.5e-23, 83.33% id in 66 aa, and to Yersinia pestis hypothetical protein ypo2890 or y1341 SWALL:Q8ZCS7 (EMBL:AJ414154) (66 aa) fasta scores: E(): 6.1e-20, 76.56% id in 64 aa. | Chaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.979 |
| ECA3231 | icsU | ECA3231 | ECA3236 | Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yfhj or b2524 or z3791 or ecs3390 or sf2571 SWALL:AAN44070 (EMBL:M88654) (66 aa) fasta scores: E(): 3.5e-23, 83.33% id in 66 aa, and to Yersinia pestis hypothetical protein ypo2890 or y1341 SWALL:Q8ZCS7 (EMBL:AJ414154) (66 aa) fasta scores: E(): 6.1e-20, 76.56% id in 64 aa. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.883 |
| ECA3231 | iscS | ECA3231 | ECA3237 | Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yfhj or b2524 or z3791 or ecs3390 or sf2571 SWALL:AAN44070 (EMBL:M88654) (66 aa) fasta scores: E(): 3.5e-23, 83.33% id in 66 aa, and to Yersinia pestis hypothetical protein ypo2890 or y1341 SWALL:Q8ZCS7 (EMBL:AJ414154) (66 aa) fasta scores: E(): 6.1e-20, 76.56% id in 64 aa. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.839 |
| ECA3231 | nifU | ECA3231 | ECA2946 | Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yfhj or b2524 or z3791 or ecs3390 or sf2571 SWALL:AAN44070 (EMBL:M88654) (66 aa) fasta scores: E(): 3.5e-23, 83.33% id in 66 aa, and to Yersinia pestis hypothetical protein ypo2890 or y1341 SWALL:Q8ZCS7 (EMBL:AJ414154) (66 aa) fasta scores: E(): 6.1e-20, 76.56% id in 64 aa. | Nitrogen fixation protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.720 |
| dnaJ | groL | ECA3881 | ECA0625 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.988 |
| dnaJ | grpE | ECA3881 | ECA0842 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.996 |
| dnaJ | hscA | ECA3881 | ECA3233 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.986 |
| dnaJ | hscB | ECA3881 | ECA3234 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.589 |
| dnaJ | htpG | ECA3881 | ECA1179 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein; Molecular chaperone. Has ATPase activity. | 0.994 |
| dnaJ | icsU | ECA3881 | ECA3236 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.470 |
| dnaJ | iscS | ECA3881 | ECA3237 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.500 |
| dnaJ | nifU | ECA3881 | ECA2946 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Nitrogen fixation protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.422 |
| fdx | ECA3231 | ECA3232 | ECA3231 | Ferredoxin, 2Fe-2S; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ferredoxin, 2fe-2s Fdx or b2525 or z3792 or ecs3391 or sf2572 SWALL:AAN44071 (EMBL:M88654) (111 aa) fasta scores: E(): 6.7e-39, 84.68% id in 111 aa. | Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yfhj or b2524 or z3791 or ecs3390 or sf2571 SWALL:AAN44070 (EMBL:M88654) (66 aa) fasta scores: E(): 3.5e-23, 83.33% id in 66 aa, and to Yersinia pestis hypothetical protein ypo2890 or y1341 SWALL:Q8ZCS7 (EMBL:AJ414154) (66 aa) fasta scores: E(): 6.1e-20, 76.56% id in 64 aa. | 0.998 |
| fdx | hscA | ECA3232 | ECA3233 | Ferredoxin, 2Fe-2S; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ferredoxin, 2fe-2s Fdx or b2525 or z3792 or ecs3391 or sf2572 SWALL:AAN44071 (EMBL:M88654) (111 aa) fasta scores: E(): 6.7e-39, 84.68% id in 111 aa. | Chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.986 |
| fdx | hscB | ECA3232 | ECA3234 | Ferredoxin, 2Fe-2S; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ferredoxin, 2fe-2s Fdx or b2525 or z3792 or ecs3391 or sf2572 SWALL:AAN44071 (EMBL:M88654) (111 aa) fasta scores: E(): 6.7e-39, 84.68% id in 111 aa. | Chaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.996 |
| fdx | icsU | ECA3232 | ECA3236 | Ferredoxin, 2Fe-2S; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ferredoxin, 2fe-2s Fdx or b2525 or z3792 or ecs3391 or sf2572 SWALL:AAN44071 (EMBL:M88654) (111 aa) fasta scores: E(): 6.7e-39, 84.68% id in 111 aa. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.968 |
| fdx | iscS | ECA3232 | ECA3237 | Ferredoxin, 2Fe-2S; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ferredoxin, 2fe-2s Fdx or b2525 or z3792 or ecs3391 or sf2572 SWALL:AAN44071 (EMBL:M88654) (111 aa) fasta scores: E(): 6.7e-39, 84.68% id in 111 aa. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.950 |
| fdx | nifU | ECA3232 | ECA2946 | Ferredoxin, 2Fe-2S; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ferredoxin, 2fe-2s Fdx or b2525 or z3792 or ecs3391 or sf2572 SWALL:AAN44071 (EMBL:M88654) (111 aa) fasta scores: E(): 6.7e-39, 84.68% id in 111 aa. | Nitrogen fixation protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.864 |
