STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
suhBInositol-1-monophosphatase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 inositol-1-monophosphatase SuhB or SsyA or b2533 or c3059 or z3800 or ecs3399 SWALL:SUHB_ECOLI (SWALL:P22783) (267 aa) fasta scores: E(): 2.4e-90, 84.64% id in 267 aa. (267 aa)    
Predicted Functional Partners:
idhA
Similar to Rhizobium meliloti myo-inositol 2-dehydrogenase IdhA or rb1194 or smb20899 SWALL:MI2D_RHIME (SWALL:O68965) (330 aa) fasta scores: E(): 4.2e-59, 49.84% id in 323 aa, and to Brucella melitensis myo-inositol 2-dehydrogenase bmeii0574 SWALL:Q8YCF6 (EMBL:AE009694) (334 aa) fasta scores: E(): 1.7e-60, 51.07% id in 325 aa.
    
 0.905
ecfK
Putative surface antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
 
  
 0.647
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
  
 0.611
trmJ
Putative RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
 
     0.611
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
 
 0.610
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
   0.604
nusG
Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Bel [...]
   
 
 0.602
nusA
N utilization substance protein A; Participates in both transcription termination and antitermination.
   
   0.589
hisB
Similar to Escherichia coli histidine biosynthesis bifunctional protein HisB [includes: histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase] HisB or b2022 SWALL:HIS7_ECOLI (SWALL:P06987) (355 aa) fasta scores: E(): 1.6e-119, 82.81% id in 355 aa.
  
  
 0.580
typA
Similar to Escherichia coli GTP-binding protein TypA or BipA or b3871 SWALL:TYPA_ECOLI (SWALL:P32132) (591 aa) fasta scores: E(): 1.1e-189, 90.18% id in 591 aa. Found to be a virulence regulator in an enteropathogenic Escherichia coli (PMID: 9622352).
  
  
 0.563
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.