Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA3257Similar to Yersinia pestis two-component system sensor kinase ypo2916 or y1313 SWALL:Q8ZCQ5 (EMBL:AJ414154) (483 aa) fasta scores: E(): 5.4e-148, 79.91% id in 478 aa, and to Salmonella typhimurium putative sensory kinase in regulatory system yfhk or stm2564 SWALL:Q8ZN30 (EMBL:AE008816) (480 aa) fasta scores: E(): 6.7e-134, 73.67% id in 471 aa. (478 aa)    
Predicted Functional Partners:
ECA3255
Similar to Yersinia pestis two-component system response regulator ypo2914 SWALL:Q8ZCQ7 (EMBL:AJ414154) (445 aa) fasta scores: E(): 1.3e-149, 91.91% id in 445 aa, and to Salmonella typhimurium putative transcriptional regulator of two-component regulator protein yfha or stm2562 SWALL:Q8ZN32 (EMBL:AE008816) (445 aa) fasta scores: E(): 1.3e-142, 86.96% id in 445 aa.
 
 
 0.995
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
 0.988
ECA3256
Similar to Yersinia pestis putative lipoprotein ypo2915 SWALL:Q8ZCQ6 (EMBL:AJ414154) (331 aa) fasta scores: E(): 7.9e-37, 45.45% id in 253 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yfhg or b2555 or z3831 or ecs3421 or sf2602 SWALL:YFHG_ECOLI (SWALL:P37328) (237 aa) fasta scores: E(): 3.6e-30, 45.61% id in 228 aa.
 
 
 
 0.965
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.945
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
  
 0.922
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
  
 0.884
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
 
 0.786
pspC
Phage shock protein C; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri phage shock protein C PspC or b1306 or c1777 or z2479 or ecs1883 or sf1311 SWALL:PSPC_ECOLI (SWALL:P23855) (119 aa) fasta scores: E(): 1.5e-25, 63.15% id in 114 aa.
  
   0.760
rof
Modulator of rho-dependent transcription termination; Similar to Escherichia coli, and Shigella flexneri Rof protein or b0189 or sf0179 SWALL:ROF_ECOLI (SWALL:P52098) (84 aa) fasta scores: E(): 3.4e-22, 70.23% id in 84 aa, and to Salmonella typhimurium modulator of rho-dependent transcription termination Rof or stm0237 SWALL:Q8ZRN4 (EMBL:AE008706) (86 aa) fasta scores: E(): 2.9e-20, 66.27% id in 86 aa.
  
     0.731
ECA2003
Putative exported protein; Similar to Yersinia pestis hypothetical protein y2005 SWALL:AAM85571 (EMBL:AE013803) (898 aa) fasta scores: E(): 1e-188, 52.6% id in 865 aa, and to Escherichia coli O6 hypothetical protein ydbh or c1828 SWALL:AAN80292 (EMBL:AE016760) (879 aa) fasta scores: E(): 2.9e-148, 44.01% id in 861 aa.
  
    0.729
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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